ArticleJournal of the American Chemical Society2022
Synergistic Hydrolysis of Cellulose by a Blend of Cellulase-Mimicking Polymeric Nanoparticle Catalysts.
Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 48 citations in OpenAlex.
- Inhibition of protein-protein interactions among tubulinsRSC advances · 2026Article
- Direct synthesis of molecularly imprinted nanozymes with a biomimetic catalytic motif for glycosidic bond cleavage.Frontiers in chemistry · 2026Article
- Review
- Molecularly Imprinted Nanozymes for Selective Hydrolysis of Aromatic Carbonates Under Mild Conditions.Nanomaterials (Basel, Switzerland) · 2025Article
- Dual-frequency ultrasonic-assisted enzymolysis for synthesis of microstructure regulated biomass-derived porous carbon for high-performance supercapacitors.Ultrasonics sonochemistry · 2025Article
- Selective Hydrolysis of Heterooligosaccharides by Poly(acrylate) Gel Catalysts.ACS catalysis · 2024Article
- Developing Catalysts for the Hydrolysis of Glycosidic Bonds in Oligosaccharides Using a Spectrophotometric Screening Assay.ACS catalysis · 2024Article
- Opportunities and challenges for plastic depolymerization by biomimetic catalysis.Chemical science · 2024Review
- Enhanced molecular recognition with longer chain crosslinkers in molecularly imprinted polymers for an efficient separation of TR active substances.RSC advances · 2024Article
- Synthetic Catalysts for Selective Glycan Cleavage from Glycoproteins and Cells.Journal of the American Chemical Society · 2024Article
- Rational Design and Synthesis of an Artificial Enzyme for SOrganic letters · 2024Article
- Carbonic anhydrase mimics with rationally designed active sites for fine-tuned catalytic activity and selectivity in ester hydrolysis.Catalysis science & technology · 2023Article
- Supramolecular Regulation of Catalytic Activity in Molecularly Responsive Catalysts.The Journal of organic chemistry · 2023Article
- Artificial Esterase for Cooperative Catalysis of Ester Hydrolysis at pH 7.Materials today. Chemistry · 2023Article
- Selective Hydrolysis of Nonactivated Aryl Esters at pH 7 through Cooperative Catalysis.The Journal of organic chemistry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Enzyme-like catalysts by design have been a long sought-after goal of chemists but difficult to realize due to the challenges in the construction of multifunctionalized active sites with accurately positioned catalytic groups for complex substrates. Hydrolysis of cellulose is a key step in biomass utilization and requires multiple enzymes to work in concert to overcome the difficulty associated with hydrolyzing the recalcitrant substrate. We here report methods to construct synthetic versions of these enzymes through covalent molecular imprinting and strategic postmodification of the imprinted sites. The synthetic catalysts cleave a cellulose chain endolytically at multiple positions or exolytically from the nonreducing end by one or three glucose units at a time, all using the dicarboxylic acid motif found in natural cellulases. By mimicking the endocellulase, exocellulase, and β-glucosidase, the synthetic catalysts hydrolyze cellulose in a synergistic manner, with an activity at 90 °C in pH 6.5 buffer more than doubled that of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.