Evidence map›Paper›PMID 36069449›Full record

ArticlemBio2022

Bidirectional Interactions between Arboviruses and the Bacterial and Viral Microbiota in Aedes aegypti and Culex quinquefasciatus.

Chenyan Shi, Leen Beller, Lanjiao Wang, Ana Rosales Rosas, Lander De Coninck, Lyza Héry, Laurence Mousson, Nonito Pagès, Jeroen Raes, Leen Delang and 3 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Microbiota variation inMicrobiology spectrum · 2026
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  8. Viruses · 2024
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  9. Viruses · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Chenyan ShiDepartment of Preventive Medicine, School of Public Health, Shenzhen University, Shenzhen, China.ORCID 0000-0002-1898-4170
Leen BellerKU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Clinical and Epidemiological Virology, Laboratory of Viral Metagenomics, Leuven, Belgium.
Lanjiao WangKU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Researchgrid.415751.3, Laboratory of Virology and Chemotherapy, Leuven, Belgium.ORCID 0000-0002-5699-1443
Ana Rosales RosasKU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Researchgrid.415751.3, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Lander De ConinckKU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Clinical and Epidemiological Virology, Laboratory of Viral Metagenomics, Leuven, Belgium.
Lyza HéryLaboratory of Vector Control Research, Institute Pasteur of Guadeloupe-Lieu-dit Morne Jolivière, Les Abymes, Guadeloupe, France.
Laurence MoussonArboviruses and Insect Vectors Unit, Institut Pasteurgrid.428999.7, Paris, France.
Nonito PagèsCIRAD, UMR ASTRE, Petit-Bourg, Guadeloupe, France.
Jeroen RaesDepartment of Microbiology and Immunology, Rega Institute, KU Leuven-University of Leuven, Leuven, Belgium.ORCID 0000-0002-1337-041X
Leen DelangKU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Researchgrid.415751.3, Laboratory of Virology and Chemotherapy, Leuven, Belgium.ORCID 0000-0002-8874-675X
Anubis Vega-RúaLaboratory of Vector Control Research, Institute Pasteur of Guadeloupe-Lieu-dit Morne Jolivière, Les Abymes, Guadeloupe, France.
Anna-Bella FaillouxArboviruses and Insect Vectors Unit, Institut Pasteurgrid.428999.7, Paris, France.ORCID 0000-0001-6890-0820
Jelle MatthijnssensKU Leuven, Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Clinical and Epidemiological Virology, Laboratory of Viral Metagenomics, Leuven, Belgium.ORCID 0000-0003-1188-9733
Rega Institute for Medical Research · BEInstitut Pasteur · FRInstitut Pasteur de la Guadeloupe · GPCentre de Coopération Internationale en Recherche Agronomique pour le Développement · FRShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mosquitoes are important vectors for many arboviruses. It is becoming increasingly clear that various symbiotic microorganisms (including bacteria and insect-specific viruses; ISVs) in mosquitoes have the potential to modulate the ability of mosquitoes to transmit arboviruses. In this study, we compared the bacteriome and virome (both eukaryotic viruses and bacteriophages) of female adult Aedes aegypti and Culex quinquefasciatus mosquitoes fed with sucrose/water, blood, or blood spiked with Zika virus (ZIKV) or West Nile virus (WNV), respectively. Furthermore, we investigated associations between the microbiota and vector competence. We show that the influence of arboviruses on the mosquito microbiome-and vice versa-is distinct for each combination of arbovirus/mosquito species. The presence of ZIKV resulted in a temporarily increased

Indexed as

AedesArbovirusesCulexMicrobiotaVirusesWest Nile virusZika VirusZika Virus InfectionAnimalsBacteriaFemaleHumansMosquito VectorsSucroseWaterSucroseWaterarbovirusmicrobiomemosquito-arbovirus-microbiota interactionphageomesingle mosquito metagenomicsvirome

Identifiers

PMID36069449
PMCPMC9600335
OpenAlexW4297613856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.