Evidence map›Paper›PMID 36069444›Full record

ArticlemBio2022

Deciphering Cellodextrin and Glucose Uptake in

Fei Yan, Sheng Dong, Ya-Jun Liu, Xingzhe Yao, Chao Chen, Yan Xiao, Edward A Bayer, Yuval Shoham, Chun You, Qiu Cui and 1 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Fei Yan *CAS Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technologygrid.458500.c, Chinese Academy of Sciences, Qingdao, China.
Sheng Dong *CAS Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technologygrid.458500.c, Chinese Academy of Sciences, Qingdao, China.
Ya-Jun Liu *CAS Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technologygrid.458500.c, Chinese Academy of Sciences, Qingdao, China.
Xingzhe YaoCAS Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technologygrid.458500.c, Chinese Academy of Sciences, Qingdao, China.
Chao ChenCAS Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technologygrid.458500.c, Chinese Academy of Sciences, Qingdao, China.
Yan XiaoCAS Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technologygrid.458500.c, Chinese Academy of Sciences, Qingdao, China.
Edward A BayerDepartment of Biomolecular Sciences, The Weizmann Institute of Sciencegrid.13992.30, Rehovot, Israel.ORCID 0000-0001-7749-5150
Yuval ShohamDepartment of Biotechnology and Food Engineering, Technion-Israel Institute of Technology, Haifa, Israel.
Chun YouTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China.
Qiu CuiCAS Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technologygrid.458500.c, Chinese Academy of Sciences, Qingdao, China.
Yingang FengCAS Key Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technologygrid.458500.c, Chinese Academy of Sciences, Qingdao, China.ORCID 0000-0002-0879-1316
Chinese Academy of Sciences · CNBen-Gurion University of the Negev · ILTechnion – Israel Institute of Technology · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sugar uptake is of great significance in industrially relevant microorganisms. Clostridium thermocellum has extensive potential in lignocellulose biorefineries as an environmentally prominent, thermophilic, cellulolytic bacterium. The bacterium employs five putative ATP-binding cassette transporters which purportedly take up cellulose hydrolysates. Here, we first applied combined genetic manipulations and biophysical titration experiments to decipher the key glucose and cellodextrin transporters.

Indexed as

Acetivibrio thermocellusAdenosine TriphosphatasesAdenosine TriphosphateATP-Binding Cassette TransportersCellobioseCelluloseDextrinsGlucoseGlucose Transport Proteins, FacilitativeNucleotidesAdenosine TriphosphatasesAdenosine TriphosphateATP-Binding Cassette TransportersCellobiosecellodextrinCelluloseDextrinsGlucoseGlucose Transport Proteins, FacilitativeNucleotidesABC transportercellulosomegenetic inactivationprotein structuresugar-binding protein

Identifiers

PMID36069444
PMCPMC9601137
OpenAlexW4294921690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.