Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
8 authors at 1 institution in 1 country.
Jane X YehJohns Hopkins Bloomberg School of Public Health, W. Harry Feinstone Department of Molecular Microbiology and Immunology, Baltimore, Maryland, USA.
Yunfan FanJohns Hopkins Universitygrid.21107.35 Whiting School of Engineering, Department of Biomedical Engineering, Baltimore, Maryland, USA.
Maggie L BartlettJohns Hopkins Bloomberg School of Public Health, W. Harry Feinstone Department of Molecular Microbiology and Immunology, Baltimore, Maryland, USA.
Xiaoyan ZhangJohns Hopkins Bloomberg School of Public Health, W. Harry Feinstone Department of Molecular Microbiology and Immunology, Baltimore, Maryland, USA.
Norah SadowskiJohns Hopkins Universitygrid.21107.35 Whiting School of Engineering, Department of Biomedical Engineering, Baltimore, Maryland, USA.
Debra A HauerJohns Hopkins Bloomberg School of Public Health, W. Harry Feinstone Department of Molecular Microbiology and Immunology, Baltimore, Maryland, USA.
Winston TimpJohns Hopkins Universitygrid.21107.35 Whiting School of Engineering, Department of Biomedical Engineering, Baltimore, Maryland, USA.ORCID 0000-0003-2083-6027
Diane E GriffinJohns Hopkins Bloomberg School of Public Health, W. Harry Feinstone Department of Molecular Microbiology and Immunology, Baltimore, Maryland, USA.
Johns Hopkins University · US
Funding
Training: Molecular & Cellular Bases of Infectious DiseasesT32AI007417 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Arturo Casadevall · 1994 to 2026
$11.9M
CONTROL OF ALPHAVIRUS REPLICATION IN THE NERVOUS SYSTEMR01NS038932 · NINDS · JOHNS HOPKINS UNIVERSITY · PI GRIFFIN, DIANE E · 2001 to 2016
$4.9M
Direct nanopore detection of modified RNA to probe structure and dynamicsR01HG010538 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI TIMP, WINSTON GEORGE · 2019 to 2022
$3.1M
Malaria and Mosquito/Tick-borne DiseasesT32AI138953 · NIAID · JOHNS HOPKINS UNIVERSITY · PI DAVID Joseph SULLIVAN · 2019 to 2026
$2.0M
Role of CD4 T cells in fatal alphavisus encephalomyelitisR01NS087539 · NINDS · JOHNS HOPKINS UNIVERSITY · PI GRIFFIN, DIANE E · 2014 to 2018
$1.9M
Cellular Signaling Pathways Involved in Antibody-Mediated Clearance of Sindbis Virus from NeuronsF31NS101824 · NINDS · JOHNS HOPKINS UNIVERSITY · PI YEH, JANE XIE · 2018 to 2019
Alphaviruses are positive-sense RNA viruses that are important causes of viral encephalomyelitis. Sindbis virus (SINV), the prototype alphavirus, preferentially infects neurons in mice and is a model system for studying mechanisms of viral clearance from the nervous system. Antibody specific to the SINV E2 glycoprotein plays an important role in SINV clearance, and this effect is reproduced in cultures of infected mature neurons. To determine how anti-E2 antibody affects SINV RNA synthesis, Oxford Nanopore Technologies direct long-read RNA sequencing was used to sequence viral RNAs following antibody treatment of infected neurons. Differentiated AP-7 rat olfactory neuronal cells, an
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Treatment of Sindbis Virus-Infected Neurons with Antibody to E2 Alters Synthesis of Complete and nsP1-Expressing Defective Viral RNAs. · full record | OpenQuestion