ArticleJournal of Yeungnam medical science2023
Cerebral fat embolism syndrome: diagnostic challenges and catastrophic outcomes: a case series.
Article in Journal of Yeungnam medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Fulminant cerebral fat embolism syndrome initially sparing the lungs after long-bone fractures: a case report of refractory status epilepticus.Frontiers in medicine · 2026Article
- Review
- Severe Traumatic Cerebral Fat Embolism Following Pelvic Fracture: A Case Report and Literature Review.Korean journal of neurotrauma · 2025Article
- Micro-Embolic Events and Their Clearing in the Brain. A Narrative Review.Acta physiologica (Oxford, England) · 2025Review
- Fat Embolism Syndrome Treated with Methylprednisolone.Internal medicine (Tokyo, Japan) · 2025Article
- Extracorporeal Membrane Oxygenation Use in Fat Embolism Syndrome: Current Perspectives and Clinical Insights (A 20-Year Review).Journal of clinical medicine · 2025Review
- Pathophysiology, clinical manifestations, and prognostic insights of cerebral fat embolism: a literature review.Frontiers in neurology · 2025Review
- Article
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Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fat embolism syndrome is a rare but alarming, life-threatening clinical condition attributed to fat emboli entering the circulation. It usually occurs as a complication of long-bone fractures and joint reconstruction surgery. Neurological manifestations usually occur 12 to 72 hours after the initial insult. These neurological complications include cerebral infarction, spinal cord ischemia, hemorrhagic stroke, seizures, and coma. Other features include an acute confusional state, autonomic dysfunction, and retinal ischemia. In this case series, we describe three patients with fat embolism syndrome who presented with atypical symptoms and signs and with unusual neuroimaging findings. Cerebral fat embolism may occur without any respiratory or dermatological signs. In these cases, diagnosis is established after excluding other differential diagnoses. Neuroimaging using brain magnetic resonance imaging is of paramount importance in establishing a diagnosis. Aggressive hemodynamic and respiratory support from the beginning and consideration of orthopedic surgical intervention within the first 24 hours after trauma are critical to decreased morbidity and mortality.
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