Evidence map›Paper›PMID 36068574›Full record

ArticleCost effectiveness and resource allocation : C/E2022

Costs and cost-effectiveness of HIV counselling and testing modalities in Southern Mozambique.

Jun Hao Choo, Elisa Lopez-Varela, Laura Fuente-Soro, Orvalho Augusto, Charfudin Sacoor, Ariel Nhacolo, Stanley Wei, Denise Naniche, Ranjeeta Thomas, Elisa Sicuri

Abstract read
In one paragraph

Article in Cost effectiveness and resource allocation : C/E, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jun Hao ChooDepartment of Infectious Disease Epidemiology, School of Public Health, Faculty of Medicine, Imperial College London, London, UK. jhc1317@ic.ac.uk.ORCID http://orcid.org/0000-0003-3803-8488
Elisa Lopez-VarelaISGlobal, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Laura Fuente-SoroISGlobal, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Orvalho AugustoCentro de Investigação Em Saúde de Manhiça (CISM), Maputo, Mozambique.
Charfudin SacoorCentro de Investigação Em Saúde de Manhiça (CISM), Maputo, Mozambique.
Ariel NhacoloCentro de Investigação Em Saúde de Manhiça (CISM), Maputo, Mozambique.
Stanley WeiCenters for Disease Control (CDC), Center for Global Health (CGH), Division of Global HIV & TB (DGHT), Maputo, Mozambique.
Denise NanicheISGlobal, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Ranjeeta ThomasDepartment of Infectious Disease Epidemiology, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.
Elisa SicuriDepartment of Infectious Disease Epidemiology, School of Public Health, Faculty of Medicine, Imperial College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDespite the high HIV associated burden, Mozambique lacks data on HIV counselling and testing (HCT) costs. To help guide national HIV/AIDS programs, we estimated the cost per test for voluntary counselling and testing (VCT) from the patient's perspective and the costs per person tested and per HIV-positive individual linked to care to the healthcare provider for VCT, provider-initiated counselling and testing (PICT) and home-based testing (HBT). We also assessed the cost-effectiveness of these strategies for linking patients to care.

methodsData from a cohort study conducted in the Manhiça District were used to derive costs and linkage-to-care outcomes of the three HCT strategies. A decision tree was used to model HCT costs according to the likelihood of HCT linking individuals to care and to obtain the incremental cost-effectiveness ratios (ICERs) of PICT and HBT with VCT as the comparator. Sensitivity analyses were performed to assess robustness of base-case findings.

findingsBased on costs and valuations in 2015, average and median VCT costs to the patient per individual tested were US$1.34 and US$1.08, respectively. Costs per individual tested were greatest for HBT (US$11.07), followed by VCT (US$7.79), and PICT (US$7.14). The costs per HIV-positive individual linked to care followed a similar trend. PICT was not cost-effective in comparison with VCT at a willingness-to-accept threshold of US$4.53, but only marginally given a corresponding base-case ICER of US$4.15, while HBT was dominated, with higher costs and lower impact than VCT. Base-case results for the comparison between PICT and VCT presented great uncertainty, whereas findings for HBT were robust.

conclusionPICT and VCT are likely equally cost-effective in Manhiça. We recommend that VCT be offered as the predominant HCT strategy in Mozambique, but expansion of PICT could be considered in limited-resource areas. HBT without facilitated linkage or reduced costs is unlikely to be cost-effective.

Indexed as

Acquired immunodeficiency syndromeCost–benefit analysisCounselingDecision treesHealth resourcesMozambiqueUncertainty

Identifiers

PMID36068574
PMCPMC9447341

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.