ArticleScientific reports2022
Effect of artifacts upon the pressure reactivity index.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Data for Machine Learning Models: Clinical Experience Determines Interrater Reliability in Waveform Anomaly Detection.Neurocritical care · 2026Article
- Intercerebral autoregulation index consistency in the derivation of CPPopt, MAPopt, and BISopt in humans: A scoping review.Physiological reports · 2025Article
- Personalizing the Pressure Reactivity Index for Quantifying Cerebral Autoregulation in Neurocritical Care.IEEE transactions on bio-medical engineering · 2025Article
- Artifact management methodologies for arterial blood pressure signals: A systematic scoping review of human and animal literature.Physiological reports · 2025Article
- CPPopt on Medical Devices: The Imitation Game.Neurocritical care · 2024Article
- Artifact Management for Cerebral Near-Infrared Spectroscopy Signals: A Systematic Scoping Review.Bioengineering (Basel, Switzerland) · 2024Article
- Cerebral autoregulation, spreading depolarization, and implications for targeted therapy in brain injury and ischemia.Reviews in the neurosciences · 2024Review
- Evaluation of Morlet Wavelet Analysis for Artifact Detection in Low-Frequency Commercial Near-Infrared Spectroscopy Systems.Bioengineering (Basel, Switzerland) · 2023Article
- Continuous monitoring of the lower limit of reactivity in traumatic brain injury patients: understanding what is feasible.Critical care (London, England) · 2023Article
- The pressure reactivity index as a measure of cerebral autoregulation and its application in traumatic brain injury management.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2023Review
- Eight rules for the haemodynamic management of traumatic brain-injured patients.European journal of anaesthesiology and intensive care · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pressure reactivity index (PRx) is a parameter for the assessment of cerebrovascular autoregulation, but its calculation is affected by artifacts in the source biosignals-intracranial pressure (ICP) and arterial blood pressure. We sought to describe the most common short-duration artifacts and their effect on the PRx. A retrospective analysis of 935 h of multimodal monitoring data was conducted, and five types of artifacts, characterized by their shape, duration, and amplitude, were identified: rectangular, fast impulse, isoline drift, saw tooth, and constant ICP value. Subsequently, all types of artifacts were mathematically modeled and inserted into undisturbed segments of biosignals. Fast impulse, the most common artifact, did not alter the PRx index significantly when inserted into one or both signals. Artifacts present in one signal exceeded the threshold PRx in less than 5% of samples, except for isoline drift. Compared to that, the shortest rectangular artifact inserted into both signals changed PRx to a value above the set threshold in 55.4% of cases. Our analysis shows that the effect of individual artifacts on the PRx index is variable, depending on their occurrence in one or both signals, duration, and shape. This different effect suggests that potentially not all artifacts need to be removed.
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