Evidence map›Paper›PMID 36068263›Full record

SynthesisScientific reports2022

12-month prevalence of atopic dermatitis in resource-rich countries: a systematic review and meta-analysis.

Annika Volke, Karolin Toompere, Kaja-Triin Laisaar, Marje Oona, Anna Tisler, Annika Johannson, Kadi Kallavus, Katrin Lang, Ele Kiisk, Anneli Uusküla

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Salivary OMICS factors associated with atopic dermatitis in early infancy.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Incidence and Prevalence of Childhood Atopic Diseases in Dutch Primary Care.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025
    Article
  11. Review
  12. Infantile atopic dermatitis and maternal-infant bonding: a mixed methods study.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Annika VolkeDepartment of Dermatology, Institute of Clinical Medicine, University of Tartu, Raja 31, 50417, Tartu, Estonia. annika.volke@ut.ee.
Karolin ToompereInstitute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Kaja-Triin LaisaarInstitute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Marje OonaInstitute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Anna TislerInstitute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Annika JohannsonInstitute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Kadi KallavusInstitute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Katrin LangInstitute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Ele KiiskInstitute of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Anneli UuskülaDermatology Clinic, Tartu University Hospital, Tartu, Estonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a lack of robust prevalence estimates of atopic dermatitis (AD) globally and trends over time due to wide variation of populations and age groups studied, different study methodologies and case definitions used. We sought to characterize 12-month AD prevalence across the life span and change over time in resource-rich countries focusing on population-based studies and using a standardized AD case definition. This systematic review was conducted according to PRISMA guidelines. Medline (Ovid), Embase, WOS core collection, Cinahl, and Popline were searched for studies published since inception through August 15, 2016. Studies were synthesized using random effects meta-analysis. Sources of heterogeneity were investigated using subgroup analyses and meta-regression. From 12,530 records identified, 45 studies met the inclusion criteria. Meta-analysis with random effects revealed the 12-month period prevalence of 9.2% (95% confidence interval 8.4-10.1%). The prevalence was significantly higher among 0-5-year-old children (16.2%; 95% confidence interval 14.2-18.7%) than in older age groups. Studies using a random sampling strategy yielded lower prevalence estimates than studies relying on other sampling methods. There was no clear time trend in AD prevalence over the period of 1992-2013.

Indexed as

Dermatitis, AtopicAgedChild, PreschoolHumansPrevalence

Identifiers

PMID36068263
PMCPMC9448775

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.