Evidence map›Paper›PMID 36067705›Full record

ReviewMicrobiological research2022

RNA editing in Mycobacterium tuberculosis.

Yan Guo, Yuri F van der Heijden, Fernanda Maruri, Limin Jiang, Robert Morrison, Timothy R Sterling

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Microbiological research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Yan GuoDepartment of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.
Yuri F van der HeijdenDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA; Vanderbilt Tuberculosis Center, Vanderbilt University School of Medicine, Nashville, TN, USA; The Aurum Institute, Johannesburg, South Africa.
Fernanda MaruriDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA; Vanderbilt Tuberculosis Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
Limin JiangDepartment of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.
Robert MorrisonSeattle Children's Hospital, Seattle, WA, USA.
Timothy R SterlingDivision of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA; Vanderbilt Tuberculosis Center, Vanderbilt University School of Medicine, Nashville, TN, USA. Electronic address: timothy.sterling@vumc.org.
University of New Mexico · USVanderbilt University · USAurum Institute · ZASeattle Children's Hospital · US

Funding

WOMEN'S CANCERS RESEARCH PROGRAMP30CA118100 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Yolanda Sanchez · 2005 to 2026
$57.1M
Fluoroquinolone Resistance in M. TuberculosisR01AI063200 · NIAID · VANDERBILT UNIVERSITY · PI STERLING, TIMOTHY R · 2006 to 2010
$1.8M
Fluoroquinolone resistance in patients with multidrug-resistant tuberculosisK08AI106420 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI VAN DER HEIJDEN, YURI F. · 2014 to 2018
$848k
Fluoroquinolones and Efflux-Mediated Cross Resistance in HIV-related TBR56AI118361 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SHERMAN, DAVID R, STERLING, TIMOTHY R · 2016 to 2016
$696k
NCI NIH HHS P30 CA118100NIAID NIH HHS K08 AI106420NIAID NIH HHS R01 AI063200NIAID NIH HHS R56 AI118361
6 · The paper itself

Abstract

RNA editing, while studied thoroughly in humans, has been sporadically described in bacteria, and to our knowledge, has not been reported in Mycobacterium tuberculosis (Mtb). After thorough quality control and validation by repeated sequencing, by comparing sequences from RNA and DNA from high-throughput sequencing data, we report the first finding of three RNA editing events in two Mtb isolates.

Indexed as

Mycobacterium tuberculosisHigh-Throughput Nucleotide SequencingHumansRNA EditingM. tuberculosisRNA editing

Identifiers

PMID36067705
PMCPMC11332325
OpenAlexW4292730067

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.