ArticleProceedings of the National Academy of Sciences of the United States of America2022
Microbial functional diversity across biogeochemical provinces in the central Pacific Ocean.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 37 citations in OpenAlex.
- Divergent assembly patterns of core and non-core microbial taxa under low environmental heterogeneity in the surface waters of the Xisha Islands.Microbiology spectrum · 2026Article
- Genomic Survey of Carbon Monoxide Dehydrogenases Reveals Their Widespread Distribution in Marine Habitats.Environmental microbiology reports · 2026Article
- Microbial and small zooplankton communities predict density of baleen whales in the southern California Current Ecosystem.PloS one · 2026Article
- The iron metalloproteome of Pseudomonas aeruginosa under oxic and anoxic conditions.Metallomics : integrated biometal science · 2025Article
- The microbiologist's guide to metaproteomics.iMeta · 2025Review
- Picoplankton nitrogen guilds in the tropical and subtropical oceans: From the surface to the deep.PloS one · 2025Article
- Microeukaryote metabolism across the western North Atlantic Ocean revealed through autonomous underwater profiling.Nature communications · 2024Article
- Metaproteomic analysis decodes trophic interactions of microorganisms in the dark ocean.Nature communications · 2024Article
- Global biogeography of microbes driving ocean ecological status under climate change.Nature communications · 2024Article
- Functional vertical connectivity of microbial communities in the ocean.Science advances · 2024Article
- Nitrite-oxidizing bacteria adapted to low-oxygen conditions dominate nitrite oxidation in marine oxygen minimum zones.The ISME journal · 2024Article
- Prochlorococcus marinus responses to light and oxygen.PloS one · 2024Article
- The Diversity and Metabolism of Culturable Nitrate-Reducing Bacteria from the Photic Zone of the Western North Pacific Ocean.Microbial ecology · 2023Article
- Metaproteogenomic Profile of a Mesopelagic Adenylylsulfate Reductase: Course-Based Discovery Using the Ocean Protein Portal.Journal of proteome research · 2023Article
- Partitioning of the denitrification pathway and other nitrite metabolisms within global oxygen deficient zones.ISME communications · 2023Article
- Microbial functional diversity across biogeochemical provinces in the central Pacific Ocean.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Enzymes catalyze key reactions within Earth's life-sustaining biogeochemical cycles. Here, we use metaproteomics to examine the enzymatic capabilities of the microbial community (0.2 to 3 µm) along a 5,000-km-long, 1-km-deep transect in the central Pacific Ocean. Eighty-five percent of total protein abundance was of bacterial origin, with Archaea contributing 1.6%. Over 2,000 functional KEGG Ontology (KO) groups were identified, yet only 25 KO groups contributed over half of the protein abundance, simultaneously indicating abundant key functions and a long tail of diverse functions. Vertical attenuation of individual proteins displayed stratification of nutrient transport, carbon utilization, and environmental stress. The microbial community also varied along horizontal scales, shaped by environmental features specific to the oligotrophic North Pacific Subtropical Gyre, the oxygen-depleted Eastern Tropical North Pacific, and nutrient-rich equatorial upwelling. Some of the most abundant proteins were associated with nitrification and C1 metabolisms, with observed interactions between these pathways. The oxidoreductases nitrite oxidoreductase (NxrAB), nitrite reductase (NirK), ammonia monooxygenase (AmoABC), manganese oxidase (MnxG), formate dehydrogenase (FdoGH and FDH), and carbon monoxide dehydrogenase (CoxLM) displayed distributions indicative of biogeochemical status such as oxidative or nutritional stress, with the potential to be more sensitive than chemical sensors. Enzymes that mediate transformations of atmospheric gases like CO, CO
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