Observational studyThe oncologist2022
Prognostic Awareness and Discussions of Incurability in Patients with Pretreated Non-Small Cell Lung Cancer and Caregivers: A Prospective Cohort Study.
Observational study in The oncologist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Association between family-perceived quality of death and dying, prognostic awareness, and end-of-life discussions in five common diseases: a nationwide mortality follow-back study.BMC palliative care · 2026Article
- Patient-caregiver concordance on death preparedness over Taiwanese cancer patients' last 6 months.The oncologist · 2025Article
- Depression, performance status, and discontinued treatment mediate an association of curability belief with prognosis in advanced cancer patients.Scientific reports · 2024Article
- Unrealistic expectations and disclosure of incurability in patients with non-small cell lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- The trajectory of prognostic cognition in patients with advanced cancer: is the traditional advance care planning approach desirable for patients?Japanese journal of clinical oncology · 2024Review
- Goals of Care Among Patients With Advanced Cancer and Their Family Caregivers in the Last Years of Life.JAMA network open · 2024Article
- Elements of End-of-Life Discussions Associated With Patients' Reported Outcomes and Actual End-of-Life Care in Patients With Pretreated Lung Cancer.The oncologist · 2024Observational
- Expectations concerning cancer treatment: perspectives of medical oncologists and patients on advanced, unresectable lung carcinoma.Frontiers in psychology · 2024Article
- Clinicians' Prediction of Survival Is Most Useful for Palliative Care Referral.Palliative medicine reports · 2024Article
- Communication in Cancer Care in Asia: A Narrative Review.JCO global oncology · 2023Review
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough patients with advanced cancer often have poor prognostic awareness, the most effective communication approach for improving prognostic awareness is unclear. In addition, the association between prognostic awareness and preferences for future medical treatment remains unexplored. MATERIALS AND
methodsWe performed a prospective observational study of consecutive patients with advanced or post-operative recurrent non-small cell lung cancer whose disease had progressed after first-line chemotherapy, and their caregivers. We evaluated patterns of clinical discussions about incurability, prognostic awareness, and preference for future medical treatment at baseline and 3 months later.
resultsWe obtained 200 valid responses to the questionnaires at baseline and 147 valid responses 3 months later. In addition, 180 caregivers returned valid responses. A total of 54% of patients and 51% of caregivers had accurate awareness at baseline, and 52% of patients had accurate awareness 3 months later. Multiple logistic regression analysis revealed that patients who were informed about incurability in recent and past discussions were significantly more likely to have accurate awareness 3 months later, compared with those who were only informed recently (adjusted odds ratio 5.08; 95% CI, 1.31-19.78; P = .019). Accurate awareness at 3 months was significantly negatively associated with preference for life-prolonging treatment at 3 months after adjusting for covariates (adjusted odds ratio 0.39; 95% CI, 0.17-0.90; P = .028).
conclusionPatients with advanced cancer who had both recent and past discussions about incurability with their oncologists have more accurate prognostic awareness. Improving prognostic awareness could reduce the preference for life-prolonging treatment.
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