Evidence map›Paper›PMID 36067194›Full record

ArticlePloS one2022

Validity of smartphone-based retinal photography (PEEK-retina) compared to the standard ophthalmic fundus camera in diagnosing diabetic retinopathy in Uganda: A cross-sectional study.

Ahmed Mohamud Yusuf, Rebecca Claire Lusobya, John Mukisa, Charles Batte, Damalie Nakanjako, Otiti Juliet-Sengeri

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ahmed Mohamud YusufDepartment of Ophthalmology, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Rebecca Claire LusobyaDepartment of Ophthalmology, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID 0000-0002-7149-703X
John MukisaDepartment of Immunology and Molecular Biology, School of Biomedical Sciences, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID 0000-0002-9208-0313
Charles BatteDepartment of Medicine, Lung Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
Damalie NakanjakoDepartment of Medicine, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.ORCID 0000-0002-0935-2112
Otiti Juliet-SengeriDepartment of Ophthalmology, School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Makerere University · UG

Funding

Training in noncommunicable diseases epidemiological, data science and Implementation Science research to strengthen evidence-based interventions, policy and control in Uganda.D43TW011401 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI Charles Batte, William Checkley · 2019 to 2026
$1.8M
FIC NIH HHS D43 TW011401
6 · The paper itself

Abstract

introductionDiabetic retinopathy (DR) is one of the major complications of diabetes mellitus and is a significant cause of blindness worldwide. In Uganda, the prevalence of diabetes is approximately 2.7% of the urban population and 1% in rural areas. Many diabetics cannot access an eye exam due to the lack of less costly and user-friendly equipment that primary eye workers can use. Smartphone-based fundus photography allows for a cheap and mobile fundus examination. The study aimed to determine the sensitivity and specificity of the Portable Eye Examination Kit (PEEK) retina compared to a standard ophthalmic fundus camera (Zeiss Visucam 200) for the diagnosis of DR.

methodsFrom January-March 2020, 286 people with diabetes (type 1 & 2) patients were seen at Kiruddu National referral hospital diabetes clinic. All participants had funduscopy with PEEK retina and the standard ophthalmic fundus camera following ophthalmic examination and pupillary dilation. The PEEK retina's sensitivity, specificity and reliability were determined using an ophthalmic fundus camera as the gold standard.

resultsThe participants' mean age was 51 with a standard deviation of ±11years, 213 (74.5%) were females, and the majority (93.4%) had Type 2 diabetes. The overall Sensitivity of PEEK retina for DR was 84% (95% CI 70.9-83.5), while the specificity was 79.9% (95% CI 76-83.5) with a positive predictive value (PPV) of 30.9% (95% CI 23.2-39.4) and a negative predictive value (NPV) of 97.9% (95% CI 95.9-99.1).

conclusionsPEEK retina has high sensitivity and specificity, making it suitable for screening and diagnostic purposes. Therefore, we recommend the integration of the PEEK retina in the screening and diagnosis of DR in resource-limited settings.

Indexed as

Diabetes Mellitus, Type 2Diabetic RetinopathyBenzophenonesCross-Sectional StudiesFemaleHumansMaleMass ScreeningMiddle AgedPhotographyPolymersReproducibility of ResultsRetinaSmartphoneUgandaBenzophenonespolyetheretherketonePolymers

Identifiers

PMID36067194
PMCPMC9447889
OpenAlexW4294798271

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.