Evidence map›Paper›PMID 36066862›Full record

Trial reportJournal of consulting and clinical psychology2022

Mechanisms of quality-of-life improvement in treatment for alcohol use disorder.

Hannah A Carlon, Margo C Hurlocker, Katie Witkiewitz

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hannah A CarlonDepartment of Psychology, Center on Alcohol, Substance Use, and Addictions, University of New Mexico.ORCID 0000-0003-2624-9392
Margo C HurlockerDepartment of Psychology, Center on Alcohol, Substance Use, and Addictions, University of New Mexico.ORCID 0000-0002-9744-8551
Katie WitkiewitzDepartment of Psychology, Center on Alcohol, Substance Use, and Addictions, University of New Mexico.ORCID 0000-0002-1086-3067
Canadian Centre on Substance Use and Addiction · CA

Funding

Alcohol Research Training: Methods & MechanismsT32AA018108 · NIAAA · UNIVERSITY OF NEW MEXICO · PI Katie A Witkiewitz · 2010 to 2026
$5.6M
Precision Medicine and Recovery in a Telehealth Treatment Program for Alcohol Use DisorderR01AA022328 · NIAAA · UNIVERSITY OF NEW MEXICO · PI Katie A Witkiewitz · 2013 to 2026
$3.1M
Mechanisms of Behavior Change in Alcohol Use Disorder TreatmentR01AA025539 · NIAAA · UNIVERSITY OF NEW MEXICO · PI TOFIGHI, DAVOOD, WITKIEWITZ, KATIE A · 2017 to 2021
$2.1M
Adapting intake procedures to improve treatment delivery in addiction treatmentK23DA052646 · NIDA · UNIVERSITY OF NEW MEXICO · PI HURLOCKER, MARGO · 2021 to 2025
$869k
NIAAA NIH HHS R01 AA022328NIAAA NIH HHS R01 AA025539NIAAA NIH HHS T32 AA018108NIDA NIH HHS K23 DA052646
6 · The paper itself

Abstract

objectiveFor individuals in alcohol use disorder (AUD) treatment, many argue that holistic indicators such as quality of life (QoL) should be more consistently used in addition to drinking-related indicators. QoL increases from pre- to post-AUD treatment, but the mechanisms are unclear. The present study examined the roles of positive and negative affect in QoL change during AUD treatment and additionally explored the relationship between QoL change and medication adherence.

methodWe examined the mediating roles of end-of-treatment positive affect (i.e., vigor) and negative affect (i.e., stress and tension) in the relationship between baseline (BL) and 26-week QoL among participants in the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence study randomized to medication management (MM; n = 468) or medication management plus combined behavioral intervention (MMCBI; n = 479) for AUD. We also explored whether changes in QoL were associated with medication adherence.

resultsChange in psychological health QoL was mediated by increased vigor (i.e., positive affect) and decreased stress, and change in environmental QoL was mediated by decreased stress. There were also differences by treatment group, with stress mediating changes in environmental QoL among participants in MM, and vigor mediating changes in psychological health QoL among participants in MMCBI. Medication adherence was not associated with greater QoL after controlling for posttreatment alcohol use.

conclusionsThe present study identified potential mechanisms of QoL change in AUD treatment, thus contributing to the growing knowledge surrounding alternative indicators of treatment success for AUD treatment and recovery. Targeting affective states and stress during treatment may improve QoL and recovery outcomes for persons with AUD. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Indexed as

AlcoholismAlcohol DrinkingBehavior TherapyHumansQuality of LifeTreatment Outcome

Identifiers

PMID36066862
PMCPMC9899433
OpenAlexW4294754474

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.