Evidence map›Paper›PMID 36066606›Full record

ArticleAmerican journal of respiratory and critical care medicine2023

Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity.

Xingnan Li, Stefano Guerra, Julie G Ledford, Monica Kraft, Huashi Li, Annette T Hastie, Mario Castro, Loren C Denlinger, Serpil C Erzurum, John V Fahy and 12 more

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Genome-wide Association Study IdentifiesAllergy, asthma & immunology research · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Frontiers in immunology · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Xingnan LiDivision of Genetics, Genomics, and Precision Medicine, and.ORCID 0000-0002-1208-8658
Stefano GuerraAsthma and Airway Disease Research Center, Department of Medicine, University of Arizona, Tucson, Arizona.ORCID 0000-0001-7218-3246
Julie G LedfordAsthma and Airway Disease Research Center, Department of Medicine, University of Arizona, Tucson, Arizona.
Monica KraftAsthma and Airway Disease Research Center, Department of Medicine, University of Arizona, Tucson, Arizona.
Huashi LiDivision of Genetics, Genomics, and Precision Medicine, and.
Annette T HastieDepartment of Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.ORCID 0000-0001-6607-7797
Mario CastroDivision of Pulmonary, Critical Care, and Sleep Medicine, University of Kansas School of Medicine, Kansas City, Kansas.
Loren C DenlingerDepartment of Medicine, University of Wisconsin School of Medicine & Public Health, Madison, Wisconsin.
Serpil C ErzurumLerner Research Institute and the Respiratory Institute, Cleveland Clinic, Cleveland, Ohio.
John V FahyDivision of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of California at San Francisco, San Francisco, California.
Benjamin GastonWells Center for Pediatric Research and Riley Hospital for Children, Indiana University, Indianapolis, Indiana.
Elliot IsraelDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Nizar N JarjourDepartment of Medicine, University of Wisconsin School of Medicine & Public Health, Madison, Wisconsin.
Bruce D LevyDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.ORCID 0000-0001-9515-5731
David T MaugerDepartment of Public Health Sciences, College of Medicine, Penn State University, Hershey, Pennsylvania.
Wendy C MooreDepartment of Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Joe ZeinLerner Research Institute and the Respiratory Institute, Cleveland Clinic, Cleveland, Ohio.
Naftali KaminskiDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut; and.ORCID 0000-0001-5917-4601
Sally E WenzelDepartment of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0002-4242-0164
Prescott G WoodruffDivision of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of California at San Francisco, San Francisco, California.
Deborah A MeyersDivision of Genetics, Genomics, and Precision Medicine, and.
Eugene R BleeckerDivision of Genetics, Genomics, and Precision Medicine, and.

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Washington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4M
WORKER PROTECTION AGAINST AIRBORNE INFLUENZA - A PILOT STUDYM01RR007122 · NCRR · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KOCH, KENNETH L · 1992 to 2010
$35.2M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
ZOSUQUIDAR TRIHYDROCHLORIDE IN NEWLY DIAGNOSED AMLM01RR003186 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI SONDEL, PAUL M · 1986 to 2007
$19.3M
Rapid saliva antigen test for SARS-CoV-2 detectionU01HL146002 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ARONICA, MARK A, CASTRO, MARIO · 2019 to 2023
$17.3M
VIRALLY-INDUCED STAT-1, STAT-3 AND STAT-6M01RR018390 · NCRR · CLEVELAND CLINIC LERNER COM-CWRU · PI GILDEA, THOMAS · 2003 to 2007
$11.0M
NCATS NIH HHS UL1 TR000427NCATS NIH HHS UL1 TR001102NCATS NIH HHS UL1 TR001420NCATS NIH HHS UL1 TR001863NCATS NIH HHS UL1 TR002345NCATS NIH HHS UL1 TR002373NCATS NIH HHS UL1 TR002378NCRR NIH HHS M01 RR003186NCRR NIH HHS M01 RR007122NCRR NIH HHS M01 RR018390NCRR NIH HHS UL1 RR024992NHLBI NIH HHS K08 HL133381NHLBI NIH HHS R01 HL069116NHLBI NIH HHS R01 HL069130NHLBI NIH HHS R01 HL069149NHLBI NIH HHS R01 HL069155NHLBI NIH HHS R01 HL069167NHLBI NIH HHS R01 HL069170NHLBI NIH HHS R01 HL069174NHLBI NIH HHS R01 HL069349NHLBI NIH HHS R01 HL087665NHLBI NIH HHS R01 HL091762NHLBI NIH HHS R01 HL142769NHLBI NIH HHS RC2 HL101487NHLBI NIH HHS U01 HL146002NHLBI NIH HHS U10 HL109086NHLBI NIH HHS U10 HL109146NHLBI NIH HHS U10 HL109152NHLBI NIH HHS U10 HL109164NHLBI NIH HHS U10 HL109168NHLBI NIH HHS U10 HL109172NHLBI NIH HHS U10 HL109250NHLBI NIH HHS U10 HL109257NIAID NIH HHS R01 AI135108NIAID NIH HHS R01 AI149754
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaUteroglobinBiomarkersEpithelial CellsHumansInflammationProspective StudiesRetrospective StudiesRNA, MessengerBiomarkersRNA, MessengerSCGB1A1 protein, humanUteroglobinasthma exacerbationsasthma severitybronchial epithelial cellsCC16T2 inflammation

Identifiers

PMID36066606
PMCPMC9940145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.