Evidence map›Paper›PMID 36066554›Full record

ArticleEmerging microbes & infections2022

Determinants of fluconazole resistance and echinocandin tolerance in

Farnaz Daneshnia, João N de Almeida Júnior, Amir Arastehfar, Lisa Lombardi, Erika Shor, Lis Moreno, Ana Verena Mendes, Maria Goreth Barberino, Danilo Thomaz Yamamoto, Geraldine Butler and 2 more

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  4. Review
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  9. Threats from theMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Analysis of clinicalAntimicrobial agents and chemotherapy · 2024
    Article
  14. Article
  15. Changing Epidemiology of Clinical Isolates ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  16. Article
  17. Article
  18. Candida parapsilosis complex in the clinical setting.Nature reviews. Microbiology · 2024
    Review
  19. Analysis of clinicalbioRxiv : the preprint server for biology · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

Farnaz DaneshniaCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA.ORCID 0000-0002-8782-2036
João N de Almeida JúniorSpecial Mycology Laboratory, Federal University of São Paulo, São Paulo, Brazil.ORCID 0000-0002-3766-026X
Amir ArastehfarCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA.ORCID 0000-0002-4361-4841
Lisa LombardiSchool of Biomolecular and Biomedical Science, Conway Institute, University College Dublin, Dublin, Ireland.ORCID 0000-0002-2522-1278
Erika ShorCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA.
Lis MorenoHospital São Rafael, Salvador, Brazil.
Ana Verena MendesHospital São Rafael, Salvador, Brazil.
Maria Goreth BarberinoHospital São Rafael, Salvador, Brazil.
Danilo Thomaz YamamotoMycology Laboratory, Instituto de Medicina Tropical, Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0001-8999-5806
Geraldine ButlerSchool of Biomolecular and Biomedical Science, Conway Institute, University College Dublin, Dublin, Ireland.
David S PerlinCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA.
Arnaldo Lopes ColomboSpecial Mycology Laboratory, Federal University of São Paulo, São Paulo, Brazil.ORCID 0000-0003-0793-8491
D’Or Institute for Research and Education · BRHackensack Meridian Health · USUniversity College Dublin · IEGeorgetown University · USHospital Israelita Albert Einstein · BRUniversidade de São Paulo · BRUniversidade Federal de São Paulo · BR

Funding

Critical Factors Influencing Echinocandin Resistance in CandidaglabrataR01AI109025 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI PERLIN, DAVID S · 2014 to 2025
$9.8M
NIAID NIH HHS R01 AI109025
6 · The paper itself

Abstract

Patients presenting with severe COVID-19 are predisposed to acquire secondary fungal infections such as COVID-19-associated candidemia (CAC), which are associated with poor clinical outcomes despite antifungal treatment. The extreme burden imposed on clinical facilities during the COVID-19 pandemic has provided a permissive environment for the emergence of clonal outbreaks of multiple

Indexed as

CandidemiaCOVID-19Antifungal AgentsBrazilCandida parapsilosisDisease OutbreaksEchinocandinsFluconazoleHumansIntensive Care UnitsMicrobial Sensitivity TestsPandemicsVoriconazoleAntifungal AgentsEchinocandinsFluconazoleVoriconazoleCandida parapsilosiscandidemiaechinocandin tolerancefluconazole resistanceoutbreak

Identifiers

PMID36066554
PMCPMC9542950
OpenAlexW4294817118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.