Evidence map›Paper›PMID 36065854›Full record

ArticlePhysiological reports2022

Tetraplegia is associated with increased hypoxic ventilatory response during nonrapid eye movement sleep.

Sarah Vaughan, Abdulghani Sankari, Sean Carroll, Mehdi Eshraghi, Harold Obiakor, Hossein Yarandi, Susmita Chowdhuri, Anan Salloum, M Safwan Badr

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sarah VaughanDepartment of Medicine, John D. Dingell VA Medical Center, Detroit, Michigan, USA.ORCID 0000-0001-7962-4526
Abdulghani SankariDepartment of Medicine, John D. Dingell VA Medical Center, Detroit, Michigan, USA.ORCID 0000-0002-2400-3375
Sean CarrollDepartment of Medicine, John D. Dingell VA Medical Center, Detroit, Michigan, USA.
Mehdi EshraghiDepartment of Medicine, John D. Dingell VA Medical Center, Detroit, Michigan, USA.
Harold ObiakorDepartment of Medicine, John D. Dingell VA Medical Center, Detroit, Michigan, USA.
Hossein YarandiDepartment of Internal Medicine, Wayne State University, Detroit, Michigan, USA.
Susmita ChowdhuriDepartment of Medicine, John D. Dingell VA Medical Center, Detroit, Michigan, USA.
Anan SalloumDepartment of Medicine, John D. Dingell VA Medical Center, Detroit, Michigan, USA.
M Safwan BadrDepartment of Medicine, John D. Dingell VA Medical Center, Detroit, Michigan, USA.
Wayne State University · US

Funding

Sleep-Disordered Breathing in patients with C-SCI: Mechanisms and TherapyR01HL130552 · NHLBI · WAYNE STATE UNIVERSITY · PI BADR, M.SAFWAN · 2016 to 2020
$1.5M
Sleep disordered breathing and cardiovascular outcome: New approach and secondary analysis.R21HL140447 · NHLBI · WAYNE STATE UNIVERSITY · PI SANKARI, ABDULGHANI · 2017 to 2018
$231k
Pathophysiology-Guided Therapy for Sleep Apnea in the ElderlyI01CX001201 · VA · JOHN D DINGELL VA MEDICAL CENTER · PI CHOWDHURI, SUSMITA · 2015 to 2018
–
CSRD VA I01 CX001040CSRD VA I01 CX001201CSRD VA IK2 CX000547NHLBI NIH HHS HL130552NHLBI NIH HHS R01 HL130552NHLBI NIH HHS R21 HL140447RRD VA I21 RX002885
6 · The paper itself

Abstract

People with cervical spinal cord injury (SCI) are likely to experience chronic intermittent hypoxia while sleeping. The physiological effects of intermittent hypoxia on the respiratory system during spontaneous sleep in individuals with chronic cervical SCI are unknown. We hypothesized that individuals with cervical SCI would demonstrate higher short- and long-term ventilatory responses to acute intermittent hypoxia (AIH) exposure than individuals with thoracic SCI during sleep. Twenty participants (10 with cervical SCI [9 male] and 10 with thoracic SCI [6 male]) underwent an AIH and sham protocol during sleep. During the AIH protocol, each participant experienced 15 episodes of isocapnic hypoxia using mixed gases of 100% nitrogen (N

Indexed as

Eye MovementsSpinal Cord InjuriesHumansHypoxiaMaleQuadriplegiaSleepacute intermittent hypoxiahypoxialong-term facilitationplasticityspinal cord injury

Identifiers

PMID36065854
PMCPMC9446393
OpenAlexW4294718966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.