ArticleHypertension (Dallas, Tex. : 1979)2023
Sympathetic Action Potential Firing and Recruitment Patterns Are Abnormal in Gestational Hypertension.
Article in Hypertension (Dallas, Tex. : 1979), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- COMMENTARY on "Factors Associated with Preeclampsia and the Hypertensive Disorders of Pregnancy Amongst Indigenous Women of Canada, Australia, New Zealand and the United States: A Systematic Review and Meta-analysis" by Stephens et al. (2025) Published in Current Hypertension Reports.Current hypertension reports · 2026Article
- Stress Trajectory and Hypertension 2 to 7 Years After Delivery: A nuMoM2b-HHS Study.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Longitudinal changes in cardiovascular and sympathetic neural responses to static handgrip exercise throughout pregnancy.American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- Autonomic control of blood pressure in women: The roles of hypertension and aging.Autonomic neuroscience : basic & clinical · 2025Review
- Associations of physical activity and sedentary time with aortic stiffness and autonomic function in early pregnancy.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- Impact of maternal obesity on resting muscle sympathetic nerve activity during uncomplicated pregnancy: a longitudinal assessment.American journal of physiology. Regulatory, integrative and comparative physiology · 2024Article
- Muscle Sympathetic Action Potential Firing Patterns During Normotensive and Hypertensive Pregnancy: A Longitudinal Assessment.Circulation · 2023Article
Corrections and comments
- Commented on by
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundWe tested the hypothesis that women who develop gestational hypertension (GH) display abnormal sympathetic action potential (AP) discharge patterns during late pregnancy (32-36 weeks), both at supine rest and during postural stress.
methodsThirteen nonpregnant, female controls (nonpregnant controls [CTRL]) and 32 pregnant women participated; 14 had low-risk (no personal history of GH) normal pregnancies (LR-NP), 10 had high-risk (personal history of GH) normal pregnancies (HR-NP), and 8 developed GH. We measured heart rate, blood pressure, and muscle sympathetic nerve activity (microneurography) at supine rest and 60° head-up tilt. Sympathetic AP patterns were studied using wavelet-based methodology.
resultsAt rest, muscle sympathetic nerve activity burst frequency was elevated in LR-NP, HR-NP, and GH versus CTRL (all
conclusionsWomen who develop GH display aberrant sympathetic AP firing patterns in both the supine and upright postures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.