Evidence map›Paper›PMID 36065478›Full record

ArticleHIV medicine2023

Real-world experience with weight gain among pregnant women living with HIV who are using integrase inhibitors.

Trevon Fuller, Maria Isabel Fragoso da Silveira Gouvêa, Maria de Lourdes Benamor Teixeira, Adriana Ferreira Medeiros, Patricia Amorim da Silva, Camile Medeiros Braga, Miriam Constan Werneck Sant'anna, Mariza de Mattos Salgueiro, Clarisse da Silveira Bressan, Wallace Mendes-Silva and 1 more

Open access · greenAbstract read
In one paragraph

Article in HIV medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Trevon FullerInfectious Diseases Department, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.
Maria Isabel Fragoso da Silveira GouvêaInfectious Diseases Department, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.
Maria de Lourdes Benamor TeixeiraInfectious Diseases Department, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.
Adriana Ferreira MedeirosInfectious Diseases Department, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.
Patricia Amorim da SilvaMaternal Fetal Unit, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.
Camile Medeiros BragaInfectious Diseases Department, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.
Miriam Constan Werneck Sant'annaMaternal Fetal Unit, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.
Mariza de Mattos SalgueiroInfectious Diseases Department, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.
Clarisse da Silveira BressanInfectious Diseases Department, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.
Wallace Mendes-SilvaMaternal Fetal Unit, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.
Esau C JoãoInfectious Diseases Department, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil.ORCID 0000-0002-2412-0627
Hospital Federal dos Servidores do Estado · BRUniversity of California, Los Angeles · US

Funding

NICHD NIH HHS HHSN275201300003C
6 · The paper itself

Abstract

objectivesWe assessed real-world weight change and pregnancy outcomes among pregnant women living with HIV who used integrase strand transferase inhibitor (INSTI)-based combined antiretroviral therapy (cART).

methodsIn a retrospective cohort study from 2014 to 2021 for prevention of perinatal HIV infection, we evaluated changes in weight from the first prenatal visit to near delivery for two groups. The categories of change were: low (< 0.18 kg/week), normal (0.18-0.59 kg/week), and high (> 0.59 kg/week). The backbones were lamivudine + tenofovir disoproxil or lamivudine + zidovudine. The comparison groups were women with body mass index (BMI) < 25 kg/m

resultsWe enrolled 198 pregnant women. At study entry, 74 had BMI < 25 kg/m

conclusionsINSTI-naïve participants with BMI < 25 kg/m

Indexed as

Anti-HIV AgentsGestational Weight GainHIV InfectionsHIV IntegraseHIV Integrase InhibitorsFemaleHumansLamivudinePregnancyPregnancy OutcomePregnant PeopleRetrospective StudiesWeight GainAnti-HIV AgentsHIV IntegraseHIV Integrase InhibitorsLamivudineanti-HIV agentsgestational weight gainHIV integrase inhibitorspregnancy outcomes

Identifiers

PMID36065478
PMCPMC9985658
OpenAlexW4294808801

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.