Evidence map›Paper›PMID 36065328›Full record

ArticleMetabolic engineering communications2022

Itaconic acid production is regulated by LaeA in

Kyle R Pomraning, Ziyu Dai, Nathalie Munoz, Young-Mo Kim, Yuqian Gao, Shuang Deng, Teresa Lemmon, Marie S Swita, Jeremy D Zucker, Joonhoon Kim and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolic engineering communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Engineering of Global Transcriptional Regulators (GTRs) inJournal of fungi (Basel, Switzerland) · 2025
    Review
  2. Review
  3. Molecular regulation of fungal secondary metabolism.World journal of microbiology & biotechnology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Kyle R PomraningPacific Northwest National Laboratory, Richland, WA, USA.
Ziyu DaiPacific Northwest National Laboratory, Richland, WA, USA.
Nathalie MunozPacific Northwest National Laboratory, Richland, WA, USA.
Young-Mo KimPacific Northwest National Laboratory, Richland, WA, USA.
Yuqian GaoPacific Northwest National Laboratory, Richland, WA, USA.
Shuang DengPacific Northwest National Laboratory, Richland, WA, USA.
Teresa LemmonPacific Northwest National Laboratory, Richland, WA, USA.
Marie S SwitaPacific Northwest National Laboratory, Richland, WA, USA.
Jeremy D ZuckerPacific Northwest National Laboratory, Richland, WA, USA.
Joonhoon KimPacific Northwest National Laboratory, Richland, WA, USA.
Stephen J MondoJoint Genome Institute, Walnut Creek, CA, USA.
Ellen PaniskoPacific Northwest National Laboratory, Richland, WA, USA.
Meagan C BurnetPacific Northwest National Laboratory, Richland, WA, USA.
Bobbie-Jo M Webb-RobertsonPacific Northwest National Laboratory, Richland, WA, USA.
Beth HofstadPacific Northwest National Laboratory, Richland, WA, USA.
Scott E BakerPacific Northwest National Laboratory, Richland, WA, USA.
Kristin E Burnum-JohnsonPacific Northwest National Laboratory, Richland, WA, USA.
Jon K MagnusonPacific Northwest National Laboratory, Richland, WA, USA.
Agile BioFoundry
Pacific Northwest National Laboratory · USJoint Genome Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global regulator LaeA controls secondary metabolism in diverse Aspergillus species. Here we explored its role in regulation of itaconic acid production in

Indexed as

Aspergillus pseudoterreusItaconic acidlaeAMulti-omicsPhosphateProcess robustness

Identifiers

PMID36065328
PMCPMC9440423
OpenAlexW4292858584

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.