Evidence map›Paper›PMID 36065277›Full record

ArticleInfection and drug resistance2022

Assessing the Emergence of Resistance in vitro and Invivo: Linezolid Combined with Fosfomycin Against Fosfomycin-Sensitive and Resistant

Yaowen Li, Yu Peng, Na Zhang, Huiping Liu, Jun Mao, Yisong Yan, Shuaishuai Wang, Guang Yang, Yanyan Liu, Jiabin Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Synergistic properties of linezolid against Enterococcus spp. isolates: a systematic review from in vitro studies.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yaowen LiDepartment of Basic and Clinical Pharmacology, School of Pharmacy, Anhui Medical University, Hefei, People's Republic of China.ORCID 0000-0002-1689-1050
Yu PengDepartment of Basic and Clinical Pharmacology, School of Pharmacy, Anhui Medical University, Hefei, People's Republic of China.
Na ZhangDepartment of Basic and Clinical Pharmacology, School of Pharmacy, Anhui Medical University, Hefei, People's Republic of China.
Huiping LiuDepartment of Basic and Clinical Pharmacology, School of Pharmacy, Anhui Medical University, Hefei, People's Republic of China.
Jun MaoDepartment of Basic and Clinical Pharmacology, School of Pharmacy, Anhui Medical University, Hefei, People's Republic of China.
Yisong YanDepartment of Pharmacy, Anhui College of Traditional Chinese Medicine, Wuhu, Anhui, People's Republic of China.
Shuaishuai WangDepartment of Basic and Clinical Pharmacology, School of Pharmacy, Anhui Medical University, Hefei, People's Republic of China.
Guang YangDepartment of Pharmacy, The Third People's Hospital of Tongling, Tongling, Anhui, People's Republic of China.ORCID 0000-0002-4476-362X
Yanyan LiuDepartment of Infectious Diseases, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Jiabin LiDepartment of Infectious Diseases, The First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.
Xiaohui HuangDepartment of Basic and Clinical Pharmacology, School of Pharmacy, Anhui Medical University, Hefei, People's Republic of China.
Anhui Medical University · CNAnhui University of Traditional Chinese Medicine · CNThe People's Hospital Tongling · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We aimed to evaluate the synergistic effect of linezolid and fosfomycin on fosfomycin-sensitive and -resistant Methods: The synergistic effect of linezolid and fosfomycin was studied via in vitro checkerboard and static time-kill assays, as well as based on the in vivo survival rate and hemolymph load of a Results: In vitro and in vivo data showed that linezolid combined with fosfomycin had a good synergistic effect on Conclusion: Linezolid combined with fosfomycin had a synergistic effect on both fosfomycin-sensitive and -resistant

Indexed as

fitness costfosfomycinlinezolidresistancevirulence

Identifiers

PMID36065277
PMCPMC9440711
OpenAlexW4293462383

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.