Evidence map›Paper›PMID 36065192›Full record

ArticleiScience2022

3D bioprinting of nanoparticle-laden hydrogel scaffolds with enhanced antibacterial and imaging properties.

Andrea S Theus, Liqun Ning, Gabriella Kabboul, Boeun Hwang, Martin L Tomov, Christopher N LaRock, Holly Bauser-Heaton, Morteza Mahmoudi, Vahid Serpooshan

Open access · goldAbstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Image-Guided Cardiac Regeneration via a 3D Bioprinted Vascular Patch with Built-in CT Visibility.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Pentamidine inhibition of streptopain attenuatesbioRxiv : the preprint server for biology · 2025
    Article
  8. Heterogeneous and Composite Bioinks for 3D-Bioprinting of Complex Tissue.Biomedical materials & devices (New York, N.Y.) · 2025
    Review
  9. Review
  10. 3D Bioprinting in Limb Salvage Surgery.Journal of functional biomaterials · 2024
    Review
  11. Article
  12. Review
  13. Tracheal Tissue Engineering: Principles and State of the Art.Bioengineering (Basel, Switzerland) · 2024
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Andrea S TheusDepartment of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, GA 30322, USA.
Liqun NingDepartment of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, GA 30322, USA.
Gabriella KabboulDepartment of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, GA 30322, USA.
Boeun HwangDepartment of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, GA 30322, USA.
Martin L TomovDepartment of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, GA 30322, USA.
Christopher N LaRockDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Holly Bauser-HeatonDepartment of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, GA 30322, USA.
Morteza MahmoudiPrecision Health Program, Michigan State University, East Lansing, MI 48842, USA.
Vahid SerpooshanDepartment of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, GA 30322, USA.
Georgia Institute of Technology · USEmory University · USMichigan State University · US

Funding

Leveraging 3D bioprinted organoid constructs to pattern and model human brain developmentR01MH126195 · NIMH · EMORY UNIVERSITY · PI SERPOOSHAN, VAHID, SLOAN, STEVEN A · 2021 to 2025
$3.3M
A Nanostructured Skin Patch to Heal Chronic WoundsR01DK131417 · NIDDK · MICHIGAN STATE UNIVERSITY · PI Morteza Mahmoudi · 2022 to 2026
$2.0M
Proteolytic regulation of the Streptococcus pyogenes cell surfaceR01AI153071 · NIAID · EMORY UNIVERSITY · PI LAROCK, CHRISTOPHER N · 2021 to 2025
$1.9M
Molecular and Cellular Mechanisms of Neonatal Cardiac Development and RepairR00HL127295 · NHLBI · EMORY UNIVERSITY · PI SERPOOSHAN, VAHID · 2018 to 2020
$729k
NHLBI NIH HHS R00 HL127295NIAID NIH HHS R01 AI153071NIDDK NIH HHS R01 DK131417NIMH NIH HHS R01 MH126195
6 · The paper itself

Abstract

Biomaterial-associated microbial contaminations in biologically conducive three-dimensional (3D) tissue-engineered constructs have significantly limited the clinical applications of scaffold systems. To prevent such infections, antimicrobial biomaterials are rapidly evolving. Yet, the use of such materials in bioprinting-based approaches of scaffold fabrication has not been examined. This study introduces a new generation of bacteriostatic gelatin methacryloyl (GelMA)-based bioinks, incorporated with varying doses of antibacterial superparamagnetic iron oxide nanoparticles (SPIONs). The SPION-laden GelMA scaffolds showed significant resistance against the

Indexed as

BiomaterialsNanoparticlesTissue engineering

Identifiers

PMID36065192
PMCPMC9440295
OpenAlexW4291790782

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.