ArticleiScience2022
Plasticity after cognitive training reflected in prefrontal local field potentials.
Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Spike dynamics in primate lateral prefrontal cortex during working memory and decision-making: A fractal analysis.iScience · 2026Article
- Functional role of cell classes in monkey prefrontal cortex after learning a working memory task.Communications biology · 2025Article
- Delta-alpha/beta coupling as a signature of visual working memory in the prefrontal cortex.iScience · 2024Article
- Brain-wide human oscillatory local field potential activity during visual working memory.iScience · 2024Article
- Neuronal selectivity for stimulus information determines prefrontal LFP gamma power regardless of task execution.Communications biology · 2023Article
- Using Nonhuman Primate Models to Reverse-Engineer Prefrontal Circuit Failure Underlying Cognitive Deficits in Schizophrenia.Current topics in behavioral neurosciences · 2023Review
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Authors and funding
4 authors.
Funding
Abstract
Learning to perform a new cognitive task induces plasticity of the prefrontal cortex generally involving activation of more neurons and increases in firing rate; however, its effects on single neurons are diverse and complex. We sought to understand how training affects global measures of neural activity by recording and analyzing local field potentials (LFPs) in monkeys before and after they learned to perform working memory tasks. LFP power after training was characterized by a reduction in power in 20-40 Hz during the stimulus presentations and delay periods of the task. Both evoked power, synchronized to task events, and induced power exhibited this decrease after training. The effect was consistent across tasks requiring memory of spatial location and stimulus shape. Error trials were characterized by a lack of LFP power ramping around the fixation onset. Our results reveal signatures of cortical plasticity in LFPs associated with learning to perform cognitive tasks.
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Registered trials
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