Evidence map›Paper›PMID 36065070›Full record

ArticleEJNMMI research2022

Change in brain amyloid load and cognition in patients with amnestic mild cognitive impairment: a 3-year follow-up study.

Elina Rauhala, Jarkko Johansson, Mira Karrasch, Olli Eskola, Tuula Tolvanen, Riitta Parkkola, Kirsi A Virtanen, Juha O Rinne

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Elina Rauhala *Clinical Neurosciences, Faculty of Medicine, Turku University Hospital, University of Turku and Neurocenter, Turku, Finland.ORCID http://orcid.org/0000-0003-0341-2783
Jarkko Johansson *Turku PET Centre, Turku University Hospital, Turku, Finland.ORCID http://orcid.org/0000-0002-4501-4735
Mira KarraschDepartment of Psychology, Åbo Akademi University, Turku, Finland.ORCID http://orcid.org/0000-0002-6996-9157
Olli EskolaTurku PET Centre, University of Turku, Turku, Finland.ORCID http://orcid.org/0000-0002-9874-5662
Tuula TolvanenTurku PET Centre, University of Turku, Turku, Finland.
Riitta ParkkolaDepartment of Radiology, University of Turku and Turku University Hospital, Turku, Finland.ORCID http://orcid.org/0000-0001-8046-315X
Kirsi A VirtanenTurku PET Centre, Turku University Hospital, Turku, Finland.
Juha O RinneTurku PET Centre, Turku University Hospital, Turku, Finland. juha.rinne@tyks.fi.ORCID http://orcid.org/0000-0001-6369-0764
University of Turku · FITurku University Hospital · FIÅbo Akademi University · FI

Funding

Academy of Finland 310962
6 · The paper itself

Abstract

backgroundOur aim was to investigate the discriminative value of

methodsWe investigated the change in

results

conclusionsIn the early phase of aMCI, presence of amyloid pathology at baseline strongly predicted amyloid accumulation during follow-up, which was further paralleled by cognitive declines. Inversely, some of our patients remained amyloid negative also at the end of the study without significant change in

Indexed as

AlzheimerAmyloid PETCognitionFlutemetamolFollow-upMild cognitive impairmentPositron emission tomography

Identifiers

PMID36065070
PMCPMC9445147
OpenAlexW4294647474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.