ArticleNature communications2022
High-density electrode recordings reveal strong and specific connections between retinal ganglion cells and midbrain neurons.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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39 citing papers in PubMed.
- In Vivo Electrochemical Monitoring of Safinamide Pharmacokinetics in the Brain Explores Its Correlation With Vision-Related Neuronal Activity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Condition-Dependent Noise Correlations without Condition-Dependent Spike Counts.bioRxiv : the preprint server for biology · 2026Article
- Large-scale electrophysiology at single-spike resolution.Nature reviews. Neuroscience · 2026Review
- Sequential visual stimuli increase high frequency power in the visual cortex.Scientific reports · 2026Article
- The functional organization of retinal input to the mouse superior colliculus.bioRxiv : the preprint server for biology · 2026Article
- Extracellular Spike Waveforms: Morphology, Biophysics, and Classification Strategies.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
- Article
- Layer 5 myelination gates corticothalamic coincidence detection.Nature communications · 2025Article
- Ultra-high-density Neuropixels probes improve detection and identification in neuronal recordings.Neuron · 2025Article
- Advancing In Vitro Microfluidic Models for Pressure-Induced Retinal Ganglion Cell Degeneration: Current Insights and Future Directions from a Biomechanical Perspective.Micromachines · 2025Article
- Eye Opening Primes Synaptic Maturation by Enhancing AMPA Receptor-Mediated Transmission and Spinogenesis in the Developing Superior Colliculus.Molecular neurobiology · 2025Article
- Visual field of the ferret (Mustela putorius furo), rat (Rattus norvegicus), and tree shrew (Tupaia belangeri).Journal of vision · 2025Article
- Coordination of distinct sources of excitatory inputs enhances motion selectivity in the mouse visual thalamus.Neuron · 2025Article
- Diverse and dynamic influences of saccades on visual representations in the mouse superior colliculus.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Neuropixels reveal structure-function relationships in monkey V1bioRxiv : the preprint server for biology · 2025Article
- Genetically defined neuron types underlying visuomotor transformation in the superior colliculus.Nature reviews. Neuroscience · 2024Review
- Development and organization of the retinal orientation selectivity map.Nature communications · 2024Article
- More than expected: extracellular waveforms and functional responses in monkey LGN.bioRxiv : the preprint server for biology · 2024Article
- A deep-learning strategy to identify cell types across species from high-density extracellular recordings.bioRxiv : the preprint server for biology · 2024Article
- Measuring spatial visual loss in rats by retinotopic mapping of the superior colliculus using a novel multi-electrode array technique.Journal of neuroscience methods · 2024Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The superior colliculus is a midbrain structure that plays important roles in visually guided behaviors in mammals. Neurons in the superior colliculus receive inputs from retinal ganglion cells but how these inputs are integrated in vivo is unknown. Here, we discovered that high-density electrodes simultaneously capture the activity of retinal axons and their postsynaptic target neurons in the superior colliculus, in vivo. We show that retinal ganglion cell axons in the mouse provide a single cell precise representation of the retina as input to superior colliculus. This isomorphic mapping builds the scaffold for precise retinotopic wiring and functionally specific connection strength. Our methods are broadly applicable, which we demonstrate by recording retinal inputs in the optic tectum in zebra finches. We find common wiring rules in mice and zebra finches that provide a precise representation of the visual world encoded in retinal ganglion cells connections to neurons in retinorecipient areas.
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