Characterization of the fatty acid profile in the ventral midbrain of mice exposed to dietary imbalance between omega-6 and omega-3 fatty acids during specific life stages.

Nobuyuki Sakayori, Masanori Katakura, Susumu Setogawa, Makoto Sugita, Kazuto Kobayashi

Open access · goldAbstract read

In one paragraph

Article in BMC research notes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 88% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nobuyuki SakayoriDepartment of Physiology and Oral Physiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, 734-8553, Japan. sakayori@hiroshima-u.ac.jp.ORCID http://orcid.org/0000-0003-1611-4187

Masanori KatakuraLaboratory of Nutritional Physiology, Department of Pharmaceutical Sciences, Faculty of Pharmacy and Pharmaceutical Sciences, Josai University, Saitama, 350-0295, Japan.

Susumu SetogawaDepartment of Molecular Genetics, Institute of Biomedical Sciences, Fukushima Medical University, Fukushima, 960-1295, Japan.

Makoto SugitaDepartment of Physiology and Oral Physiology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, 734-8553, Japan.

Kazuto KobayashiDepartment of Molecular Genetics, Institute of Biomedical Sciences, Fukushima Medical University, Fukushima, 960-1295, Japan.

Fukushima Medical University · JPHiroshima University · JPJosai University · JP

Funding

Japan Society for the Promotion of Science JP17J10395Japan Society for the Promotion of Science JP21H03357

6 · The paper itself

Abstract

objectiveOmega-6 (n-6) and omega-3 (n-3) polyunsaturated fatty acids (PUFAs) are essential nutrients. Dietary imbalance between these PUFAs, in particular high in n-6 PUFAs and low in n-3 PUFAs (n-6

resultsn-6 PUFAs, especially linoleic acid, were increased in the ventral midbrain of offspring exposed to the n-6

Indexed as

Fatty AcidsFatty Acids, Omega-3AnimalsDietDocosahexaenoic AcidsFatty Acids, Omega-6FemaleFollow-Up StudiesLinoleic AcidsMaleMesencephalonMiceMice, Inbred C57BLPregnancyDocosahexaenoic AcidsFatty AcidsFatty Acids, Omega-3Fatty Acids, Omega-6Linoleic AcidsFatty acid profileLife stageMidbrainOmega-3Omega-6

Identifiers

PMID36064737

DOI10.1186/s13104-022-06175-0

PMCPMC9446585

OpenAlexW4294690250

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.