Evidence map›Paper›PMID 36064720›Full record

ArticleTrials2022

Pediatric Tuina for functional constipation in children: study protocol for a randomized controlled trail.

Xinghe Zhang, Luan Hu, Li Li, Yuanwang Wang, Can Zhang, Jinyan Su, Hua Di, Qing Gao, Xiantao Tai, Taipin Guo

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Silk-derived sericin/fibroin mixture drink fermented with plant-derivedBioscience of microbiota, food and health · 2024
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Xinghe Zhang *School of Second Clinical Medicine, Yunnan University of Chinese Medicine, Kunming, China.
Luan Hu *Department of Tuina, Yunnan Province Hospital of Traditional Chinese Medicine, Kunming, China.
Li LiDepartment of Science and Technology, Yunnan University of Chinese Medicine, Kunming, China.
Yuanwang WangSchool of Second Clinical Medicine, Yunnan University of Chinese Medicine, Kunming, China.
Can ZhangSchool of Second Clinical Medicine, Yunnan University of Chinese Medicine, Kunming, China.
Jinyan SuDepartment of Chinese Medicine, Kunming Children's Hospital, Kunming, China.
Hua DiDepartment of Acupuncture and Tuina, Zhejiang Provincial People's Hospital, Hangzhou, China.
Qing GaoDepartment of Pediatric Tuina, Shandong Province Hospital of Traditional Chinese Medicine, Jinan, China.
Xiantao Tai *School of Second Clinical Medicine, Yunnan University of Chinese Medicine, Kunming, China. taixiantao@163.com.
Taipin Guo *School of Second Clinical Medicine, Yunnan University of Chinese Medicine, Kunming, China. gtphncs@126.com.
Yunnan University · CNKunming Children's Hospital · CNSecond People's Hospital of Yunnan Province · CNYunnan Provincial Hospital of Traditional Chinese Medicine · CNZhejiang Provincial People's Hospital · CN

Funding

Special Subsidy of Yunnan Province 2020009Youth Top Talent Project of Ten-thousand Talent Plan YNWR-QNBJ-2019-257
6 · The paper itself

Abstract

backgroundFunctional constipation (FC) is a common functional gastrointestinal disorder, which brings many negative impacts to the children's daily life. Pediatric Tuina has been proved to be a potential therapy for FC. However, the evidence for its effectiveness and safety is insufficient due to the lack of high-quality study. This study aims to evaluate the efficacy and safety of pediatric Tuina for children with FC. METHODS/

designThis study is a randomized, controlled, multicentre, clinical trial. We will include 176 children with FC from five hospitals. The participants will be randomly allocated into two groups: the pediatric Tuina group and the Medilac-Vita group. This study will include a 1-week actual treatment period and a 2-week follow-up period. Primary outcomes are weekly spontaneous bowel movements and weekly complete spontaneous bowel movements. The secondary outcomes are effective rate, stool form, distress sensation, and glycerine enema rate. The assessment will be performed each week. Adverse event will be monitored in the treatment period and follow-up period. DISCUSSION: This study is designed to evaluate the efficacy and safety of pediatric Tuina for children with FC, and we hypothesize that pediatric Tuina is more effective than probiotics. It will provide reliable evidence and support for the treatment of FC by pediatric Tuina.

trial registrationThis protocol was registered in the Chinese Clinical Trial Registry (ChiCTR2100046485). .

Indexed as

ConstipationDefecationChildHumansMedicine, Chinese TraditionalMulticenter Studies as TopicQualitative ResearchRandomized Controlled Trials as TopicFunctional constipationPediatric TuinaRandomized controlled trial

Identifiers

PMID36064720
PMCPMC9446667
OpenAlexW4294647355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.