ArticleBMC medicine2022
Device-measured physical activity and incident affective disorders.
Article in BMC medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sedentary behavior and physical activity are associated with risk of depression among adult and older populations: a systematic review and dose-response meta-analysis.Frontiers in psychology · 2025Pooled it
- Device-measured and self-reported physical activity and the trajectory of cardio-renal-metabolic multimorbidity: a prospective cohort study in UK Biobank.BMC public health · 2026Article
- Accelerometer-measured physical activity, sedentary behavior, and incident neuropsychiatric diseases: a large prospective cohort study of 73411 participants.Molecular psychiatry · 2026Article
- Rest-Activity Timing Phenotypes and Mental Health: A Longitudinal Analysis of 24-Hour Accelerometry in Population-Based Cohorts.Health data science · 2026Article
- Compositional Associations of 24-h Movement Behaviors With Depressive and Anxiety Symptoms in Middle-Aged Adults.Depression and anxiety · 2026Article
- Optimal dose and pattern of physical activity to prevent diagnosed depression: prospective cohort study.Psychological medicine · 2025Article
- Dose-response relationship between physical activity and anxiety symptoms in medical students from Serbia.Frontiers in sports and active living · 2025Article
- Accelerometer-derived 'weekend warrior' physical activity pattern and brain health.Nature aging · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundStudies on physical activity (PA) and mental health are largely limited to self-reported PA. This study aims to use prospective cohort data to investigate the association between device-measured PA and affective disorders.
methodsA total of 37,327 participants from UK Biobank who had not had any prior affective disorder diagnoses were included in this prospective cohort study. Wrist-worn accelerometers were used to measure total, light (LPA), moderate (MPA), and vigorous (VPA) PA. Associations between PA domains and affective disorders were analysed using penalised splines in Cox proportional hazard models. Analyses were adjusted for other intensity-specific PA and sociodemographic and lifestyle factors. Sensitivity analyses were conducted adjusting for body mass index and longstanding illnesses as well as excluding events in the first 2 years of follow-up. Preventable fractions for the population were estimated for MPA and VPA.
resultsOver a median follow-up of 6.8 years, 1262 (3.4%) individuals were diagnosed with affective disorders. Replacing 30 min of sedentary behaviour in a week with MPA (HR 0.95, 95% CI 0.94-0.97) or VPA (HR 0.91, 95% CI 0.85-0.98) was associated with lower risk of affective behaviours, up to 500 and 120 min of MPA and VPA. Assuming causality, 5.14% and 18.88% of affective disorders could have been prevented if MPA ≥150 min/week and VPA ≥75 min/week were achieved, respectively, across the study population.
conclusionsDevice-measured MPA and VPA were associated with lower risk of affective disorders. The potential mental health benefits of MPA continue to accrue above the current World Health Organization recommendation.
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