Evidence map›Paper›PMID 36064495›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2022

A CT-based nomogram for predicting the risk of adenocarcinomas in patients with subsolid nodule according to the 2021 WHO classification.

Qilong Song, Biao Song, Xiaohu Li, Bin Wang, Yuan Li, Wu Chen, Zhaohua Wang, Xu Wang, Yongqiang Yu, Xuhong Min and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Qilong Song *Department of Radiology, Anhui Chest Hospital, Hefei, China.
Biao Song *Department of Radiology, Anhui Chest Hospital, Hefei, China.
Xiaohu Li *Department of Radiology, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Bin WangDepartment of Radiology, Anhui Chest Hospital, Hefei, China.
Yuan LiDepartment of Radiology, Anhui Chest Hospital, Hefei, China.
Wu ChenDepartment of Radiology, Anhui Chest Hospital, Hefei, China.
Zhaohua WangDepartment of Radiology, Anhui Chest Hospital, Hefei, China.
Xu WangDepartment of Radiology, Anhui Chest Hospital, Hefei, China.
Yongqiang YuDepartment of Radiology, the First Affiliated Hospital of Anhui Medical University, Hefei, China. yyq18855191201@163.com.ORCID http://orcid.org/0000-0003-4197-6846
Xuhong MinDepartment of Radiology, Anhui Chest Hospital, Hefei, China. ahch_minxuhong@163.com.
Dongchun MaClinical College of Chest, Anhui Medical University, Hefei, China. ma_dongchun@163.com.
Anhui Medical University · CNXi'an Chest Hospital · CN

Funding

Center Transfer Payment Financial Construction Project Z155080000004Natural Science Foundation of China 81771817Scientific research project of Anhui Provincial Health Commission AHWJ2021a024
6 · The paper itself

Abstract

purposeTo establish a nomogram for predicting the risk of adenocarcinomas in patients with subsolid nodules (SSNs) according to the 2021 WHO classification.

methodsA total of 656 patients who underwent SSNs resection were retrospectively enrolled. Among them, 407 patients were assigned to the derivation cohort and 249 patients were assigned to the validation cohort. Univariate and multi-variate logistic regression algorithms were utilized to identity independent risk factors of adenocarcinomas. A nomogram based on the risk factors was generated to predict the risk of adenocarcinomas. The discrimination ability of the nomogram was evaluated using the concordance index (C-index), its performance was calibrated using a calibration curve, and its clinical significance was evaluated using decision curves and clinical impact curves.

resultsLesion size, mean CT value, vascular change and lobulation were identified as independent risk factors for adenocarcinomas. The C-index of the nomogram was 0.867 (95% CI, 0.833-0.901) in derivation cohort and 0.877 (95% CI, 0.836-0.917) in validation cohort. The calibration curve showed good agreement between the predicted and actual risks. Analysis of the decision curves and clinical impact curves revealed that the nomogram had a high standardized net benefit.

conclusionsA nomogram for predicting the risk of adenocarcinomas in patients with SSNs was established in light of the 2021 WHO classification. The developed model can be adopted as a pre-operation tool to improve the surgical management of patients.

Indexed as

AdenocarcinomaNomogramsHumansRetrospective StudiesRisk FactorsTomography, X-Ray ComputedWorld Health Organization2021 WHO classificationCT featuresLung cancerNomogram model

Identifiers

PMID36064495
PMCPMC9446567
OpenAlexW4294643509

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.