Evidence map›Paper›PMID 36064355›Full record

ArticleBMC immunology2022

Cycling and activated CD8

Shuai Liu, Zhisheng Huang, Ruyue Fan, Ju Jia, Xiaoyan Deng, Xiaohui Zou, Hui Li, Bin Cao

Open access · goldAbstract read
In one paragraph

Article in BMC immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Shuai Liu *Department of Respiratory and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Zhisheng Huang *Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Ruyue FanShandong Center for Disease Control and Prevention, Jinan, Shandong, China.
Ju JiaInstitute of Respiratory Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Xiaoyan DengTsinghua University-Peking University Joint Center for Life Sciences, Tsinghua University, Beijing, China.
Xiaohui ZouInstitute of Respiratory Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Hui LiInstitute of Respiratory Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Bin CaoInstitute of Respiratory Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China. caobin_ben@163.com.
China-Japan Friendship Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNCenter for Life Sciences · CNShandong Center for Disease Control and Prevention · CNShandong First Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundT cell lymphopenia was a significant characteristic of severe influenza infection and it was associated with the functional changes of T cells. It is necessary to clarify the T cells characteristics of kinetic changes and their correlation with disease severity.

methodsIn a cohort of hospitalized influenza patients with varying degrees of severity, we characterized lymphocyte populations using flow cytometry.

resultsThe numbers of cycling (Ki67

conclusionsThe increased numbers of cycling memory (Ki67

Indexed as

HIV InfectionsInfluenza, HumanCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHLA-DR AntigensHumansKi-67 AntigenLeukocyte Common AntigensLymphocyte ActivationSeverity of Illness IndexT-Lymphocyte SubsetsHLA-DR AntigensKi-67 AntigenLeukocyte Common AntigensCell cycleSevere influenza infectionT cell function

Identifiers

PMID36064355
PMCPMC9441835
OpenAlexW4294600096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.