ArticleBMC geriatrics2022
Cardiovascular disease risk and all-cause mortality associated with accelerometer-measured physical activity and sedentary time ‒ a prospective population-based study in older adults.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Aerobic physical activity, cardiorespiratory fitness, and non-communicable diseases risk in older adults: a systematic review.BMC geriatrics · 2026Pooled it
- National Heart Center/Saudi Heart Association 2025 Guidelines for Cardiovascular Diseases Prevention and Risk Assessment.Saudi medical journal · 2026Guideline
- Combination of self-management strategies for reducing sedentary behavior with multicomponent exercise on sedentary behavior patterns and physical function in community-dwelling older adults: a randomized, blinded clinical trial with 40-week follow-up.European geriatric medicine · 2025Trial
- A Cross-Sectional Analytical Study: Prevalence and Clinical Profile of Metabolic Syndrome Among Middle Eastern, Mainly Jordanians, Cohort Presented with Atherosclerotic Cardiovascular Disease.Vascular health and risk management · 2026Observational
- Redefining atherosclerotic cardiovascular disease patients with no standard modifiable risk factors "SMuRF-less": six rather than four risk factors. Analysis from the Jordan SMuRF-less Study.Frontiers in cardiovascular medicine · 2026Article
- Comparative Effects of Adapted Taekwondo Versus Tai Chi on Health Status in Independent Older Women: A Randomized Controlled Trial.Life (Basel, Switzerland) · 2025Article
- Effects of the Prescription of Physical Exercises Mediated by Mobile Applications on the Health of Older Adults: A Systematic Review.Geriatrics (Basel, Switzerland) · 2025Review
- Association between physical activity trajectories and successful aging in middle-aged and elderly Chinese individuals: a longitudinal study.BMC public health · 2025Article
- Article
- Associations between fitness, movement behaviors, and immediate post-exercise blood pressure in older adults: A network perspective.PloS one · 2025Article
- Data Analytics in Physical Activity Studies With Accelerometers: Scoping Review.Journal of medical Internet research · 2024Article
- Is public transport a promising strategy for increasing physical activity? Evidence from a study of objectively measured public transport use and physical activity.The international journal of behavioral nutrition and physical activity · 2024Article
- Associations of physical activity intensity, frequency, duration, and volume with the incidence of sarcopenia in middle-aged and older adults: a 4-year longitudinal study in China.BMC geriatrics · 2024Article
- Prospective Associations of Different Combinations of Aerobic and Muscle-Strengthening Activity With All-Cause, Cardiovascular, and Cancer Mortality.JAMA internal medicine · 2023Article
- Association between Physical Activity Habits with Cardiometabolic Variables, Body Composition, and Physical Performance in Chilean Older Women.International journal of environmental research and public health · 2023Article
- The Impact of Physical Activity and Inactivity on Cardiovascular Risk across Women's Lifespan: An Updated Review.Journal of clinical medicine · 2023Review
- Physical Activity Over the Lifecourse and Cardiovascular Disease.Circulation research · 2023Review
- Impact of Clinical Pharmacist Running Anticoagulation Clinic in Saudi Arabia.Journal of clinical medicine · 2023Article
- Effects of socioeconomic status on physical activity and cardiovascular diseases prior to and during the COVID-19 pandemic in the older adults.Frontiers in public health · 2023Article
- Using an integrated model of the theory of planned behavior and the temporal self-regulation theory to explain physical activity in patients with coronary heart disease.Frontiers in psychology · 2023Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLow levels of physical activity (PA) and high sedentary time (ST) are common in older adults and lack of PA is a risk factor for cardiovascular disease (CVD). Knowledge about associations with accelerometer-measured PA, ST and CVD risk in older adults is insufficient. This study examines the associations of accelerometer-measured PA and ST with cardiovascular risk measured using the Framingham risk score (FRS) and all-cause mortality in older adults.
methodsA population-based sample of 660 (277 men, 383 women) older people (mean age 68.9) participated in the Oulu45 cohort study from 2013‒2015. PA and ST were measured with wrist-worn accelerometers at baseline for two weeks. Ten-year CVD risk (%) was estimated with FRS. The data for all-cause mortality were identified from the Digital and Population Data Services Agency, Finland after an average of 6.2 years follow-up. The associations between moderate to vigorous physical activity (MVPA), light physical activity (LPA), ST and FRS were analyzed using the multivariable linear regression analysis. Associations between LPA, ST and mortality were analyzed using the Cox proportional-hazard regression models.
resultsEach 10 min increase in MVPA (β = -0.779, 95% CI -1.186 to -0.371, p < 0.001) and LPA (β = -0.293, 95% CI -0.448 to -0.138, p < 0.001) was negatively associated with FRS while a 10 min increase in ST (β = 0.290, 95% CI 0.158 to 0.421, p < 0.001) was positively associated with FRS. After adjustment for waist circumference, only ST was significantly associated with FRS. Each 10 min increase in LPA was associated with 6.5% lower all-cause mortality risk (HR = 0.935, 95% CI 0.884 to 0.990, p = 0.020) and each 10 min increase in ST with 5.6% increased mortality risk (HR = 1.056, 95% CI 1.007 to 1.108, p = 0.025).
conclusionA higher amount of daily physical activity, at any intensity level, and avoidance of sedentary time are associated with reduced cardiovascular disease risk in older people. Higher time spent in light physical activity and lower sedentary time are associated with lower all-cause mortality.
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