Evidence map›Paper›PMID 36064158›Full record

ArticleExperimental gerontology2022

Frequency and factors associated with sarcopenia prediction in adult and elderly patients hospitalized for COVID-19.

Gisele Barbosa de Aguiar, Keila Fernandes Dourado, Maria Izabel Siqueira de Andrade, Ivanildo Ribeiro Domingos Júnior, João Araújo Barros-Neto, Sandra Mary Lima Vasconcelos, Marina de Moraes Vasconcelos Petribú, Cláudia Mota Dos Santos, Mayana Wanessa Santos de Moura, Claudiane Barbosa de Aguiar and 8 more

Open access · greenAbstract read
In one paragraph

Article in Experimental gerontology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Gisele Barbosa de AguiarResidency Program in Clinical Nutrition, Hospital Barão de Lucena, Academic Center of Vitória de Santo Antão, Federal University of Pernambuco (CAV/UFPE), Recife, Pernambuco, Brazil. Electronic address: giseleaguiar02@gmail.com.
Keila Fernandes DouradoResidency Program in Clinical Nutrition, Hospital Barão de Lucena, Academic Center of Vitória de Santo Antão, Federal University of Pernambuco (CAV/UFPE), Recife, Pernambuco, Brazil.
Maria Izabel Siqueira de AndradeFaculty of Nutrition of the Federal University of Alagoas (UFAL), Maceió, Alagoas, Brazil.
Ivanildo Ribeiro Domingos JúniorPostgraduate Program in Nutrition, Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
João Araújo Barros-NetoFaculty of Nutrition of the Federal University of Alagoas (UFAL), Maceió, Alagoas, Brazil.
Sandra Mary Lima VasconcelosFaculty of Nutrition of the Federal University of Alagoas (UFAL), Maceió, Alagoas, Brazil.
Marina de Moraes Vasconcelos PetribúFederal University of Pernambuco, Academic Center of Vitória de Santo Antão, Nucleus of Nutrition, Vitória de Santo Antão, Pernambuco, Brazil.
Cláudia Mota Dos SantosResidency Program in Clinical Nutrition, Hospital Barão de Lucena, Academic Center of Vitória de Santo Antão, Federal University of Pernambuco (CAV/UFPE), Recife, Pernambuco, Brazil.
Mayana Wanessa Santos de MouraResidency Program in Clinical Nutrition, Hospital Barão de Lucena, Academic Center of Vitória de Santo Antão, Federal University of Pernambuco (CAV/UFPE), Recife, Pernambuco, Brazil.
Claudiane Barbosa de AguiarPostgraduate Program in Morphotechnology, Department of Histology and Embryology, Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
Maria Isabela Xavier CamposHospital Barão de Lucena, Recife, Pernambuco, Brazil.
Emerson Rogério Costa SantiagoPostgraduate Program in Nutrition, Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
José Hélio Luna da SilvaPostgraduate Program in Nutrition, Physical Activity and Phenotypic Plasticity (PPGNAFPF), Federal University of Pernambuco, Academic Center of Vitória de Santo Antão, Vitória de Santo Antão, Pernambuco, Brazil.
Shirley Kelly Dos Santos SimõesHospital Miguel Arraes, Paulista, Pernambuco, Brazil.
Anna Carolina de Melo RodriguesHospital Miguel Arraes, Paulista, Pernambuco, Brazil.
José Carlos Domingues de França FilhoMedicine Course at Faculdade Pernambucana de Saúde (FPS), Recife, Pernambuco, Brazil.
Natália Mayara Menezes de SouzaHospital Miguel Arraes, Paulista, Pernambuco, Brazil.
Thayná Menezes SantosPostgraduate Program in Nutrition, Physical Activity and Phenotypic Plasticity (PPGNAFPF), Federal University of Pernambuco, Academic Center of Vitória de Santo Antão, Vitória de Santo Antão, Pernambuco, Brazil.
Universidade Federal de Pernambuco · BRUniversidade Federal de Alagoas · BRFaculdade Frassinetti do Recife · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with COVID-19 may develop symptoms that interfere with food intake. Systemic inflammatory response associated with physical inactivity and/or immobilization during hospital stay can induce weight and muscle loss leading to sarcopenia and worsening the clinical condition of these patients. The present study identifies the frequency and factors associated with sarcopenia prediction in adult and elderly patients hospitalized for COVID-19. It is a cohort-nested cross-sectional study on adult and elderly patients admitted to wards and intensive care units (ICUs) of 8 hospitals in a northeastern Brazilian state. The study was conducted from June 2020 to June 2021. Sociodemographic, economic, lifestyle, and current and past clinical history variables were collected. Sarcopenia prediction was determined by the Strength, Assistance in walking, Rise from a chair, Climb stairs, and Falls (SARC-F) questionnaire compiled in the Remote-Malnutrition APP (R-MAPP). Patients were diagnosed with sarcopenia when the final score ≥ 4 points. The study included 214 patients with a mean age of 61.76 ± 16.91 years, of which 52.3 % were female and 57.5 % elderly. Sarcopenia prevailed in 40.7 % of the sample. Univariate analysis showed greater probability of sarcopenia in elderly individuals, nonpractitioners of physical activities, hypertensive patients, diabetic patients, and those hospitalized in the ICU. In the multivariate model, the type of hospital admission remained associated with sarcopenia prediction, where patients admitted to the ICU were 1.43 (95 % CI: 1.04; 1.97) more likely to have sarcopenia than those undergoing clinical treatment. Sarcopenia prediction was not associated with patient outcome (discharge, transfer, or death) (p = 0.332). The study highlighted an important percentage of sarcopenia prediction in patients with COVID-19, especially those admitted to the ICU. Additional investigations should be carried out to better understand and develop early diagnostic strategies to assist in the management of sarcopenic patients with COVID-19.

Indexed as

COVID-19SarcopeniaAgedCross-Sectional StudiesFemaleHospitalizationHumansMaleSurveys and QuestionnairesBody weight lossCOVID-19Nutritional statusOutcomeSarcopenia

Identifiers

PMID36064158
PMCPMC9443615
OpenAlexW4294631798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.