Evidence map›Paper›PMID 36063785›Full record

ReviewCurrent opinion in chemical biology2022

Recent advances on human milk oligosaccharide antimicrobial activity.

Sabrina K Spicer, Jennifer A Gaddy, Steven D Townsend

Abstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  14. Antimicrobial Properties of Colostrum and Milk.Antibiotics (Basel, Switzerland) · 2024
    Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sabrina K SpicerDepartment of Chemistry, Vanderbilt University, Nashville, TN 37235, United States.
Jennifer A GaddyDepartment of Chemistry, Vanderbilt University, Nashville, TN 37235, United States.
Steven D TownsendDepartment of Chemistry, Vanderbilt University, Nashville, TN 37235, United States. Electronic address: steven.d.townsend@vanderbilt.edu.

Funding

Determining the contribution of zinc deficiency to perinatal Group B Streptococcus infectionsR01HD090061 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ARONOFF, DAVID M, GADDY, JENNIFER A · 2017 to 2021
$2.5M
Toxicant Exposure Impacts Host-pathogen interactions within the Reproductive TractI01BX005352 · VA · VETERANS HEALTH ADMINISTRATION · PI GADDY, JENNIFER A · 2021 to 2024
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BLRD VA I01 BX005352NICHD NIH HHS R01 HD090061
6 · The paper itself

Abstract

Over the past century, human health has been enhanced by antimicrobial development. Following the deployment of the first antibiotics in the 1940s, bacterial resistance evolved and has increasingly outmaneuvered even the most promising antimicrobial agents. Accordingly, increased interest has been placed on alternative methods to circumvent antimicrobial resistance evolution. In the enclosed short review, we discuss the antimicrobial properties of human breast milk with a special emphasis on human milk oligosaccharides (HMOs). We recount studies across gram-negative and gram-positive pathogens, highlighting the usage of HMOs in promoting human health and wellness.

Indexed as

Anti-Infective AgentsMilk, HumanAnti-Bacterial AgentsFemaleHumansOligosaccharidesAnti-Bacterial AgentsAnti-Infective AgentsOligosaccharidesGlycobiologyGlycoscienceHMOsHuman milkHuman milk oligosaccharides

Identifiers

PMID36063785
PMCPMC10262419

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.