Evidence map›Paper›PMID 36063639›Full record

ArticleValue in health regional issues2022

Mathematical Models for Evaluating Effectiveness and Cost-Effectiveness of Cervical Cancer Control Policies in Populations Including Women Living With Human Immunodeficiency Virus: A Scoping Review.

Rowan Iskandar, Katayoun Taghavi, Nicola Low, Wichor M Bramer, Matthias Egger, Eliane Rohner

Open access · hybridAbstract readScoping Review
In one paragraph

Article in Value in health regional issues, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 5 countries.

Rowan IskandarCenter of Excellence in Decision-Analytic Modeling and Health Economics Research, sitem-insel, Bern, Switzerland; Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland; Center for Evidence Synthesis in Health, Brown University School of Public Health, Providence, RI, USA.
Katayoun TaghaviInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Nicola LowInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Wichor M BramerMedical Library, Erasmus MC, Erasmus University Medical Centre Rotterdam, Rotterdam, The Netherlands.
Matthias EggerInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England, UK; Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.
Eliane RohnerInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland. Electronic address: eliane.rohner@ispm.unibe.ch.
Institute of Social and Preventive Medicine · CHBrown University · USErasmus University Rotterdam · NLUniversity of Bern · CHUniversity of Cape Town · ZA

Funding

Observational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9M
NIAID NIH HHS U01 AI069924
6 · The paper itself

Abstract

objectivesMathematical modeling is increasingly used to inform cervical cancer control policies, and model-based evaluations of such policies in women living with human immunodeficiency virus (HIV) are an emerging research area. We did a scoping review of published literature to identify research gaps and inform future work in this field.

methodsWe systematically searched literature up to April 2022 and included mathematical modeling studies evaluating the effectiveness or cost-effectiveness of cervical cancer prevention strategies in populations including women living with HIV. We extracted information on prevention strategies and modeling approaches.

resultsWe screened 1504 records and included 22 studies, almost half of which focused on South Africa. We found substantial between-study heterogeneity in terms of strategies assessed and modeling approaches used. Fourteen studies evaluated cervical cancer screening strategies, 7 studies assessed human papillomavirus vaccination (with or without screening), and 1 study evaluated the impact of HIV control measures on cervical cancer incidence and mortality. Thirteen conducted cost-effectiveness analyses. Markov cohort state-transition models were used most commonly (n = 12). Most studies (n = 17) modeled the effect of HIV by creating HIV-related health states. Thirteen studies performed model calibration, but 11 did not report the calibration methods used. Only 1 study stated that model code was available upon request.

conclusionsFew model-based evaluations of cervical cancer control strategies have specifically considered women living with HIV. Improvements in model transparency, by sharing information and making model code publicly available, could facilitate the utility of these evaluations for other high disease-burden countries, where they are needed for assisting policy makers.

Indexed as

HIV InfectionsPapillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsCost-Benefit AnalysisEarly Detection of CancerFemaleHIVHumansModels, TheoreticalPolicyPapillomavirus Vaccinescervical cancercomparative effectivenesscost-effectivenessHIVHPVmodelingpreventionscreeningvaccination

Identifiers

PMID36063639
PMCPMC9979336
OpenAlexW4294145186

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.