Evidence map›Paper›PMID 36063622›Full record

ArticleDrug and alcohol dependence2022

Harm reduction in the hospital: An overdose prevention site (OPS) at a Canadian hospital.

Seonaid Nolan, Salpy Kelian, Thomas Kerr, Samantha Young, Isaac Malmgren, Cher Ghafari, Scott Harrison, Evan Wood, Mark Lysyshyn, Elizabeth Holliday

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  4. Harm Reduction in Inpatient Hospital Settings: An Ethics (Principlist) Analysis.Health care analysis : HCA : journal of health philosophy and policy · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Seonaid NolanBritish Columbia Centre on Substance Use, 400-1045 Howe Street, Vancouver, V6Z 2A9 BC, Canada; Department of Medicine, University of British Columbia, St. Paul's Hospital, 553B-1081 Burrard Street, Vancouver, V6Z 1Y6 BC, Canada. Electronic address: Seonaid.nolan@bccsu.ubc.ca.
Salpy KelianBritish Columbia Centre on Substance Use, 400-1045 Howe Street, Vancouver, V6Z 2A9 BC, Canada.
Thomas KerrBritish Columbia Centre on Substance Use, 400-1045 Howe Street, Vancouver, V6Z 2A9 BC, Canada.
Samantha YoungDepartment of Medicine, University of British Columbia, St. Paul's Hospital, 553B-1081 Burrard Street, Vancouver, V6Z 1Y6 BC, Canada; Providence Health Care, 1081 Burrard Street, Vancouver, V6Z 1Y6 BC, Canada; Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, 155 College Street, 6th floor, Toronto, M5T 3M7 ON, Canada; General Internal Medicine, St. Michael's Hospital, Unity Health, 30 Bond Street, Toronto, M5B 1W8 ON, Canada.
Isaac MalmgrenGeneral Internal Medicine, St. Michael's Hospital, Unity Health, 30 Bond Street, Toronto, M5B 1W8 ON, Canada.
Cher GhafariRaincity Housing and Support Society, 616 Powell Street, Vancouver, V6A 1H4 BC, Canada.
Scott HarrisonProvidence Health Care, 1081 Burrard Street, Vancouver, V6Z 1Y6 BC, Canada.
Evan WoodBritish Columbia Centre on Substance Use, 400-1045 Howe Street, Vancouver, V6Z 2A9 BC, Canada.
Mark LysyshynVancouver Coastal Health, 800-601 West Broadway, V5Z 4C2 BC, Canada; School of Population and Public Health, University of British Columbia, 2206 East Mall, Vancouver, V6T 1Z3 BC, Canada.
Elizabeth HollidayVancouver Coastal Health, 800-601 West Broadway, V5Z 4C2 BC, Canada.

Funding

Advancing Clinical Research Training within Addiction Residency ProgramsR25DA033211 · NIDA · BOSTON MEDICAL CENTER · PI Patrick O'Connor, JEFFREY H. SAMET · 2012 to 2026
$4.2M
Mentoring the next generation of addiction clinician scientists while responding to the opioid epidemicR25DA037756 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI FAIRBAIRN, NADIA · 2014 to 2023
$3.6M
NIDA NIH HHS R25 DA033211NIDA NIH HHS R25 DA037756
6 · The paper itself

Abstract

backgroundSubstance use management in hospitals can be challenging. In response, a Canadian hospital opened an overdose prevention site (OPS) where community members and hospital inpatients can inject pre-obtained illicit drugs under supervision. This study aims to: (1) describe program utilization patterns; (2) characterize OPS visits; and (3) evaluate overdose events and related outcomes.

methodsA retrospective chart review was completed at one hospital in Vancouver, Canada. All community members and hospital inpatients who visited the OPS between May 2018 and July 2019 were included. Client measures included: hospital inpatient status, use of intravenous access line for drug injection, and substances used. Program measures included: number of visits (daily/monthly), overdose (fatal/non-fatal) events and overdose-related outcomes.

resultsOverall, 11,673 OPS visits were recorded. Monthly visits increased from 306 to 1198 between May 2018 and July 2019 respectively. On average, 26 visits occurred daily. Among all visits, 20% reported being a hospital inpatient, and 5% reported using a hospital intravenous access line for drug injection. Opioids (56%) and stimulants (24%) were the most common substances used. Overall 39 overdose events occurred - 82% required naloxone reversal, 28% required transfer to the hospital's emergency department and none were fatal. Overdose events were more common among hospital inpatients compared to community clients (6.6 vs 2.2 per 1000 visits respectively; p value = 0.046).

conclusionsThis unique OPS is an example of a hospital-based harm reduction initiative. Use of the site increased over time among both groups with no fatal overdose events occurring.

Indexed as

Drug OverdoseIllicit DrugsCanadaHarm ReductionHospitalsHumansNaloxoneNeedle-Exchange ProgramsRetrospective StudiesIllicit DrugsNaloxoneHarm reductionHospitalInjection drugsOverdose preventionSupervised consumption

Identifiers

PMID36063622
PMCPMC9970047

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.