Evidence map›Paper›PMID 36063539›Full record

ArticleVeterinary medicine and science2022

Computed tomography and magnetic resonance imaging findings in dogs with vaginal leiomyoma and leiomyosarcoma.

Toshiyuki Tanaka, Shunsuke Noguchi, Yusuke Wada, Hiroki Yamazaki, Hidetaka Nishida, Hideo Akiyoshi

Open access · goldAbstract read
In one paragraph

Article in Veterinary medicine and science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Toshiyuki TanakaLaboratory of Veterinary Surgery, Graduate School of Veterinary Science, Osaka Metropolitan University, Osaka, Japan.ORCID 0000-0002-7911-913X
Shunsuke NoguchiLaboratory of Veterinary Radiology, Graduate School of Veterinary Science, Osaka Metropolitan University, Osaka, Japan.
Yusuke WadaVeterinary Medical Center, Graduate School of Veterinary Science, Osaka Metropolitan University, Osaka, Japan.
Hiroki YamazakiLaboratory of Veterinary Internal Medicine, Department of Small Animal Clinical Sciences School of Veterinary Medicine, Rakuno Gakuen University, Hokkaido, Japan.
Hidetaka NishidaLaboratory of Veterinary Surgery, Graduate School of Veterinary Science, Osaka Metropolitan University, Osaka, Japan.
Hideo AkiyoshiLaboratory of Veterinary Surgery, Graduate School of Veterinary Science, Osaka Metropolitan University, Osaka, Japan.
Osaka Metropolitan University · JPOsaka City University · JPRakuno Gakuen University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn humans, magnetic resonance imaging (MRI) is preferred over computed tomography (CT) for the assessment of pelvic lesions. Although CT findings of several pelvic tumours have been reported in veterinary medicine, MRI findings are limited.

objectivesThe purpose of this study was to retrospectively compare the CT and MRI findings in dogs with vaginal leiomyoma and leiomyosarcoma.

methodsThis retrospective study of five dogs compared the CT and MRI findings of intrapelvic lesions, including vaginal leiomyoma (n = 4) and leiomyosarcoma (n = 1). No invasion of the surrounding tissue was detected on histopathological examination. In this retrospective study, the following parameters of CT and MRI were recorded for each dog: the border between the lesion and the adjacent pelvic organs, including the prostate, rectum or urethra; signal intensity (SI) of the lesion; enhancement pattern; presence of haemorrhage; necrosis or cystic areas and lymphadenopathy. Because SI on MRI is affected by cell density, tumour cell density was analysed using a microscope slide.

resultsIn vaginal leiomyoma, the border between the lesion and the surrounding pelvic organ tends to be clearer on MRI than on CT. In vaginal leiomyosarcoma, the border was comparable between MRI and CT. Each lesion showed heterogeneous enhancement on CT and MRI scans. In each lesion, the assessment of haemorrhage, necrosis, cystic areas and lymphadenopathy was comparable between MRI and CT. The SI of the lesion on T2WI of the vaginal leiomyoma and leiomyosarcoma were hyperintense in four cases (4/4; 100%) and mixed intense in one case (1/1; 100%), respectively. The cell density of leiomyosarcoma is higher than that of leiomyomas.

conclusionsThe SI on T2WI may be useful for differentiating leiomyoma from leiomyosarcoma. MRI may be useful to differentiate vaginal leiomyomas from leiomyosarcomas and evaluate margins.

Indexed as

Dog DiseasesLeiomyomaLeiomyosarcomaLymphadenopathyAnimalsDogsFemaleHumansMagnetic Resonance ImagingMargins of ExcisionNecrosisRetrospective StudiesTomography, X-Ray Computedcell densitycomputed tomographymagnetic resonance imagingpelvic

Identifiers

PMID36063539
PMCPMC9677356
OpenAlexW4294690487

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.