Evidence map›Paper›PMID 36063296›Full record

ArticleBulletin of experimental biology and medicine2022

Influence of Litter Reduction in the Neonatal Period at Different Times after Birth on the Parameters of Brain Development in Rats.

B Ya Ryzhavskii, D I Zhilnikov, O V Lazinskaya

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

B Ya RyzhavskiiDepartment of Histology, Embryology, and Cytology, Far Eastern State Medical University, Ministry of Health of the Russian Federation, Khabarovsk, Russia. 19151943@rambler.ru.
D I ZhilnikovDepartment of Histology, Embryology, and Cytology, Far Eastern State Medical University, Ministry of Health of the Russian Federation, Khabarovsk, Russia.
O V LazinskayaDepartment of Histology, Embryology, and Cytology, Far Eastern State Medical University, Ministry of Health of the Russian Federation, Khabarovsk, Russia.
Far Eastern State Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the brain of 5- and 14-day-old intact (control group) rats and rats of the same age from litters experimentally reduced on days 1 and 5 after birth (experimental groups). In animals of both experimental subgroups, the brain had morphological signs of advanced development: greater weight of the brain and hemisphere, greater thickness of the cortex, its molecular layer, lower numerical density of neurons in the anterior parietal and proper parietal lobes, greater sizes of neurons, their nuclei, and nucleoli in the neocortex of these zones, and increased concentration of RNA in the cytoplasm of neurons. These data suggest that the rate of brain development in rats can be accelerated under the influence of environmental changes that occur after litter reduction during the neonatal period at different times after birth.

Indexed as

NeocortexNeuronsAnimalsAnimals, NewbornFemaleLitter SizeParietal LobePregnancyRatsRNARNAaccelerationbraindevelopmentmorphometry

Identifiers

PMID36063296
OpenAlexW4294585887

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.