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ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2023

Obesity and metabolic state are associated with increased healthcare resource and medication use and costs: a Finnish population-based study.

Aino Vesikansa, Juha Mehtälä, Katja Mutanen, Annamari Lundqvist, Tiina Laatikainen, Tero Ylisaukko-Oja, Tero Saukkonen, Kirsi H Pietiläinen

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Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Association of body mass index categories with healthcare use and health expenditures in Switzerland: a cross-sectional, community-based study.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aino VesikansaMedEngine Oy, Eteläranta 14, 00130, Helsinki, Finland. aino.vesikansa@medengine.fi.
Juha MehtäläMedEngine Oy, Eteläranta 14, 00130, Helsinki, Finland.
Katja MutanenNovo Nordisk Farma Oy, Espoo, Finland.
Annamari LundqvistFinnish Institute for Health and Welfare, Helsinki, Finland.
Tiina LaatikainenFinnish Institute for Health and Welfare, Helsinki, Finland.
Tero Ylisaukko-OjaMedEngine Oy, Eteläranta 14, 00130, Helsinki, Finland.
Tero SaukkonenNovo Nordisk Farma Oy, Espoo, Finland.
Kirsi H PietiläinenObesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo characterize healthcare resource (HCRU) and medication use and associated costs in individuals with obesity compared with individuals with normal weight or overweight in a population-based cohort of Finnish adults. The association between metabolic state and direct costs was also assessed.

methodsThe study cohort included 5587 randomly selected individuals who participated in the national FinHealth 2017 health examination survey. Data on healthcare visits and hospital stays, including diagnoses (ICD-10), and purchases and costs of prescription medicines were collected from the nationwide registers by the Finnish Institute for Health and Welfare and Social Insurance Institution of Finland. The healthcare costs were calculated based on standard unit costs reported by the Finnish Institute for Health and Welfare.

resultsThe total annual direct costs were €2665 (SD €5673) and €1799 (SD €3874) per person with obesity and with normal weight or overweight, respectively. Obesity was associated with significantly increased total direct (age- and sex-adjusted cost rate ratio, RR, 1.356; p < 0.001), HCRU-related (1.273; p = 0.002), and medication (1.669; p < 0.001) costs. A vast majority (90%) of individuals with obesity were classified as metabolically unhealthy based on clinical measurements. The metabolically unhealthy state was associated with increased costs in individuals with obesity but not in individuals with normal weight or overweight.

conclusionObesity is associated with a significant and complex direct cost burden to society, arising primarily from increased comorbidity. Metabolically healthy obesity is uncommon and obesity prevention and timely treatment should be of high priority to tackle the increasing burden of obesity.

Indexed as

ObesityOverweightAdultBody Mass IndexFinlandHealth Care CostsHumansBody mass indexCostsHealthcare resource useMedication useObesity

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.