ArticleeLife2022
Molecular characteristics and laminar distribution of prefrontal neurons projecting to the mesolimbic system.
Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Chronic nicotine vapor-induced enhancement of ethanol drinking-in-the-dark is associated with reduced medial prefrontal cortical activity.Psychopharmacology · 2026Article
- Article
- Uncovering phenotypic diversity and cell-type-specific prefrontal cortex calcium dynamics in rat fentanyl self-administration.bioRxiv : the preprint server for biology · 2026Article
- A molecularly defined basalo-prefrontal-thalamic circuit regulates sensory and affective dimensions of pain in male mice.Nature communications · 2026Article
- Sex differences in noradrenergic regulation of the medial prefrontal cortex in mice.Biology of sex differences · 2025Article
- Convergence and Segregation of Excitatory and Inhibitory Afferents in the Paraventricular Thalamic Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- A consensus definition for deep layer 6 excitatory neurons in mouse somatosensory, visual, and motor cortex.Cell reports · 2025Article
- FOXP2-immunoreactive corticothalamic neurons in neocortical layers 6a and 6b are tightly regulated by neuromodulatory systems.iScience · 2025Article
- Drug-induced change in transmitter identity is a shared mechanism generating cognitive deficits.Nature communications · 2024Article
- Drug-induced change in transmitter identity is a shared mechanism generating cognitive deficits.Research square · 2023Article
- The PFC-LH-VTA pathway contributes to social deficits in IRSp53-mutant mice.Molecular psychiatry · 2023Article
- Self-supervised deep clustering of single-cell RNA-seq data to hierarchically detect rare cell populations.Briefings in bioinformatics · 2023Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prefrontal cortical influence over the mesolimbic system - including the nucleus accumbens (NAc) and the ventral tegmental area (VTA) - is implicated in various cognitive processes and behavioral malfunctions. The functional versatility of this system could be explained by an underlying anatomical complexity; however, the detailed characterization of the medial prefrontal cortical (mPFC) innervation of the NAc and VTA is still lacking. Therefore, combining classical retrograde and conditional viral tracing techniques with multiple fluorescent immunohistochemistry, we sought to deliver a precise, cell- and layer-specific anatomical description of the cortico-mesolimbic pathways in mice. We demonstrated that NAc- (mPFC
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.