ReviewAngewandte Chemie (International ed. in English)2022
How Subtle Changes Can Make a Difference: Reproducibility in Complex Supramolecular Systems.
Review in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 46 citations in OpenAlex.
- Curvature-emergent supramolecular polymerization of a porphyrin dyad with a scissor-shaped motif.Chemical science · 2026Article
- Dynamic Reconfiguration of Pt(II) Supramolecular Assemblies via Ligand Exchange.ACS applied materials & interfaces · 2025Article
- Bayesian Optimization for Multicomponent Supramolecular Systems.Journal of the American Chemical Society · 2025Article
- Evolving Data-Driven Strategies for the Characterization of Supramolecular Polymers and Systems.Angewandte Chemie (International ed. in English) · 2025Review
- Article
- Elucidating the Boundary of Intercalation vs Sequestration in Supramolecular Polymers by Retrosynthetic Design Toward the Construction of Complex Supramolecular Systems.Angewandte Chemie (International ed. in English) · 2025Article
- Synthetic chitin oligosaccharide nanocrystals and their higher-order assemblies.Chemical science · 2025Article
- Reproducibility in chemistry research.Heliyon · 2024Review
- Solvent-Induced Pathway Complexity of Supramolecular Polymerization Unveiled Using the Hansen Solubility Parameters.Journal of the American Chemical Society · 2023Article
- Self-assembly of chiral diketopyrrolopyrrole chromophores giving supramolecular chains in monolayers and twisted microtapes.Chirality · 2023Article
- Impact of sample history and solvent effects on pathway control in the supramolecular polymerisation of Au(i)-metallopeptide amphiphiles.Polymer chemistry · 2023Article
- How Subtle Changes Can Make a Difference: Reproducibility in Complex Supramolecular Systems.Angewandte Chemie (International ed. in English) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The desire to construct complex molecular systems is driven by the need for technological (r)evolution and our intrinsic curiosity to comprehend the origin of life. Supramolecular chemists tackle this challenge by combining covalent and noncovalent reactions leading to multicomponent systems with emerging complexity. However, this synthetic strategy often coincides with difficult preparation protocols and a narrow window of suitable conditions. Here, we report on unsuspected observations of our group that highlight the impact of subtle "irregularities" on supramolecular systems. Based on the effects of pathway complexity, minute amounts of water in organic solvents or small impurities in the supramolecular building block, we discuss potential pitfalls in the study of complex systems. This article is intended to draw attention to often overlooked details and to initiate an open discussion on the importance of reporting experimental details to increase reproducibility in supramolecular chemistry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.