Evidence map›Paper›PMID 36062346›Full record

ArticleMolecular oncology2022

Evaluation of two new highly multiplexed PCR assays as an alternative to next-generation sequencing for IDH1/2 mutation detection.

Loetitia Favre, Nouhoum Sako, Sihem Tarfi, Violaine Tran Quang, Corine Joy, Aurélie Dupuy, Erell Guillerm, Philippe Gaulard, Orianne Wagner-Ballon, Anaïs Pujals and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecular oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Outcome of Metastatic Biliary Tract Cancer HarbouringJournal of clinical medicine · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Loetitia FavreDepartment of Pathology, AP-HP, Henri Mondor University Hospital, Creteil, France.ORCID 0000-0001-8786-5960
Nouhoum SakoDepartment of Pathology, AP-HP, Henri Mondor University Hospital, Creteil, France.
Sihem TarfiUniv Paris Est Creteil, INSERM, IMRB, France.
Violaine Tran QuangUniv Paris Est Creteil, INSERM, IMRB, France.
Corine JoyHematology and Immunology Department, AP-HP, Henri Mondor University Hospital, Creteil, France.
Aurélie DupuyUniv Paris Est Creteil, INSERM, IMRB, France.
Erell GuillermGenetic Department, AP-HP, University Hospital Pitié Salpêtrière, Paris, France.
Philippe GaulardDepartment of Pathology, AP-HP, Henri Mondor University Hospital, Creteil, France.
Orianne Wagner-BallonUniv Paris Est Creteil, INSERM, IMRB, France.
Anaïs PujalsDepartment of Pathology, AP-HP, Henri Mondor University Hospital, Creteil, France.ORCID 0000-0002-3452-7420
Ivan SlomaUniv Paris Est Creteil, INSERM, IMRB, France.ORCID 0000-0001-8585-0861
Inserm · FRAssistance Publique – Hôpitaux de Paris · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IDH1 and IDH2 somatic mutations have been identified in solid tumors and blood malignancies. The development of inhibitors of mutant IDH1 and IDH2 in the past few years has prompted the development of a fast and sensitive assay to detect IDH1

Indexed as

High-Throughput Nucleotide SequencingIsocitrate DehydrogenaseGene FrequencyHumansMutationPolymerase Chain ReactionIDH1 protein, humanIsocitrate DehydrogenasecancerddPCRIDH1/2leukemiaNGSqPCR

Identifiers

PMID36062346
PMCPMC9718115
OpenAlexW4294580052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.