Evidence map›Paper›PMID 36062330›Full record

ArticleThe FEBS journal2023

Unexpected expansion of the voltage-gated proton channel family.

Gustavo Chaves, Artem G Ayuyan, Vladimir V Cherny, Deri Morgan, Arne Franzen, Lynne Fieber, Lydia Nausch, Christian Derst, Iryna Mahorivska, Christophe Jardin and 2 more

Abstract read
In one paragraph

Article in The FEBS journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Modulators of the Human Voltage-Gated Proton Channel HPharmaceuticals (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Transcendent Aspects of Proton Channels.Annual review of physiology · 2024
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Gustavo ChavesCenter of Physiology, Pathophysiology and Biophysics, Paracelsus Medical University, Nuremberg, Germany.
Artem G AyuyanDepartment of Physiology & Biophysics, Rush University, Chicago, IL, USA.
Vladimir V ChernyDepartment of Physiology & Biophysics, Rush University, Chicago, IL, USA.
Deri MorganDepartment of Radiation Oncology, University of Kansas Medical Center, MO, USA.
Arne FranzenInstitute of Biological Information Processing, Molecular and Cellular Physiology (IBI-1), Jülich, Germany.
Lynne FieberDepartment of Marine Biology and Ecology - Rosenstiel School of Marine and Atmospheric Science, Miami, FL, USA.
Lydia NauschCenter of Physiology, Pathophysiology and Biophysics, Paracelsus Medical University, Nuremberg, Germany.
Christian DerstCenter of Physiology, Pathophysiology and Biophysics, Paracelsus Medical University, Nuremberg, Germany.
Iryna MahorivskaCenter of Physiology, Pathophysiology and Biophysics, Paracelsus Medical University, Nuremberg, Germany.
Christophe JardinCenter of Physiology, Pathophysiology and Biophysics, Paracelsus Medical University, Nuremberg, Germany.
Thomas E DeCourseyDepartment of Physiology & Biophysics, Rush University, Chicago, IL, USA.
Boris MussetCenter of Physiology, Pathophysiology and Biophysics, Paracelsus Medical University, Nuremberg, Germany.ORCID 0000-0001-8242-8817

Funding

The National Resource for Aplysia-Curation & Informatics.P40OD010952 · OD · UNIVERSITY OF MIAMI ROSENTEIL SCHOOL · PI M Danielle McDonald · 2012 to 2026
$10.7M
Control Mechanisms of Human Voltage Gated Proton Channels, hHv1R35GM126902 · NIGMS · RUSH UNIVERSITY MEDICAL CENTER · PI DECOURSEY, THOMAS E · 2018 to 2022
$1.8M
NIGMS NIH HHS R35 GM126902NIH HHS P40 OD010952
6 · The paper itself

Abstract

Voltage-gated ion channels, whose first identified function was to generate action potentials, are divided into subfamilies with numerous members. The family of voltage-gated proton channels (H

Indexed as

Ion Channel GatingProtonsAnimalsArginineCytosolIon ChannelsMammalsArginineIon ChannelsProtonsAplysia californicamolluscpatch-clampprotonvoltage-gating

Identifiers

PMID36062330
PMCPMC10911540

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.