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ArticleJournal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)2022

A Challenging Diagnosis of Sheehan's Syndrome in Non-obstetric Critical Care and Emergency Settings: A Case Series of Five Patients with Varied Presentations.

Suhail Sarwar Siddiqui, Nibu Dominic, Sukriti Kumar, Kauser Usman, Sai Saran, Avinash Agrawal, Mohan Gurjar, Syed Nabeel Muzaffar

Abstract read
In one paragraph

Article in Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Endocrine Disorders in Critically Ill Patients - The Smooth Criminal?Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Suhail Sarwar SiddiquiDepartment of Critical Care Medicine, King George Medical University, Lucknow, Uttar Pradesh, India.
Nibu DominicDepartment of Endocrinology, Aster Medcity, Kochi, Kerala, India.
Sukriti KumarDepartment of Radiodiagnosis, King George Medical University, Lucknow, Uttar Pradesh, India.
Kauser UsmanEndocrinology Division, King George Medical University, Lucknow, Uttar Pradesh, India.
Sai SaranDepartment of Critical Care Medicine, King George Medical University, Lucknow, Uttar Pradesh, India.
Avinash AgrawalDepartment of Critical Care Medicine, King George Medical University, Lucknow, Uttar Pradesh, India.
Mohan GurjarDepartment of Critical Care Medicine, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Syed Nabeel MuzaffarDepartment of Critical Care Medicine, King George Medical University, Lucknow, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sheehan's syndrome is a life-threatening endocrine emergency seen in postpartum females secondary to ischemic pituitary necrosis. It is a frequent cause of hypopituitarism in developing countries that occurs secondary to postpartum haemorrhage (PPH). Patients with Sheehan's syndrome often present with organ dysfunctions in critical care settings, secondary to stressors precipitating the underlying hormonal deficiencies. The initial clinical picture of Sheehan's syndrome may mimic some other disease, leading to misdiagnosis and diagnostic delay. Strict vigilance, timely diagnosis, and appropriate management are essential to avoid diagnostic delay and to improve the patient outcome. In this case series, we describe 5 cases of previously undiagnosed Sheehan's syndrome (including young, middle aged and postmenopausal females) that presented to critical care and emergency settings with organ failures.

Indexed as

hypopituitarismpituitary necrosispostpartum haemorrhageSheehan’s syndrome

Identifiers

PMID36062035
PMCPMC9396951

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.