Evidence map›Paper›PMID 36062022›Full record

ReviewFrontiers in neurology2022

Application of extracorporeal shock wave therapy in nervous system diseases: A review.

Juan Guo, Hong Hai, Yuewen Ma

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07070661 (Effects of Radial Pressure Wave Therapy Modulation in Patients With Carpal Tunnel Syndrome), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07070661 nacompletednot on this mapstarted 2025, after this paper: background citation

Effects of Radial Pressure Wave Therapy Modulation in Patients With Carpal Tunnel Syndrome: A Double-Blind Randomized Clinical Trial.

TypeinterventionalSponsorArmando Tonatiuh Avila GarciaRan2025 to 2026Enrolled60ConditionsCarpal Tunnel Syndrome (CTS)ArmsFixed-Dose Radial Pressure Wave Therapy., Modulated-Dose Radial Pressure Wave Therapy.
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Extracorporeal shockwave therapy in tissue repair and regeneration.Wiener medizinische Wochenschrift (1946) · 2026
    Review
  4. Peripheral nerve repair: innovations and future directions.Journal of translational medicine · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Efficacy of Extracorporeal Shockwave Therapy for Postherpetic Neuralgia.Pain practice : the official journal of World Institute of Pain · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Emerging theory of sensitization in post-stroke muscle spasticity.Frontiers in rehabilitation sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Juan GuoDepartment of Rehabilitation Medicine, The First Affiliated Hospital of China Medical University, Shenyang, China.
Hong HaiDepartment of Rehabilitation Medicine, The First Affiliated Hospital of China Medical University, Shenyang, China.
Yuewen MaDepartment of Rehabilitation Medicine, The First Affiliated Hospital of China Medical University, Shenyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurological disorders are one of the leading causes of morbidity and mortality worldwide, and their therapeutic options remain limited. Recent animal and clinical studies have shown the potential of extracorporeal shock wave therapy (ESWT) as an innovative, safe, and cost-effective option to treat neurological disorders. Moreover, the cellular and molecular mechanism of ESWT has been proposed to better understand the regeneration and repairment of neurological disorders by ESWT. In this review, we discuss the principles of ESWT, the animal and clinical studies involving the use of ESWT to treat central and peripheral nervous system diseases, and the proposed cellular and molecular mechanism of ESWT. We also discuss the challenges encountered when applying ESWT to the human brain and spinal cord and the new potential applications of ESWT in treating neurological disorders.

Indexed as

central nervous system diseasescost-effectivenessextracorporeal shock wave therapymechanotransductionneural tissue regenerationperipheral nervous system diseases

Identifiers

PMID36062022
PMCPMC9428455

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.