Evidence map›Paper›PMID 36061865›Full record

ArticleFrontiers in cellular and infection microbiology2022

Rapid diagnosis of

Madhu Puri, Harsimran Kaur Brar, Evanka Madan, Rajesh Srinivasan, Kapil Rawat, Sai Siva Gorthi, Geeta Kumari, Raj Sah, Sashi Bhusan Ojha, Subhendu Panigrahi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Madhu PuriSchool of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Harsimran Kaur BrarSchool of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Evanka MadanSchool of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Rajesh SrinivasanDepartment of Instrumentation and Applied Physics, Indian Institute of Science, Bengaluru, India.
Kapil RawatDepartment of Instrumentation and Applied Physics, Indian Institute of Science, Bengaluru, India.
Sai Siva GorthiDepartment of Instrumentation and Applied Physics, Indian Institute of Science, Bengaluru, India.
Geeta KumariSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.
Raj SahSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.
Sashi Bhusan OjhaDepartment of Biotechnology, Maharaja Sriram Chandra Bhanjadeo University, Baripada, India.
Subhendu PanigrahiDepartment of General Medicine, VSS Medical College and Hospital, Sambalpur, India.
Gunanidhi DhangadamajhiDepartment of Biotechnology, Maharaja Sriram Chandra Bhanjadeo University, Baripada, India.
Rohini MuthuswamiSchool of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Shailja SinghSpecial Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, India.
Rentala MadhubalaSchool of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Jawaharlal Nehru University · INIndian Institute of Science Bangalore · INMaharaja Sriram Chandra Bhanja Deo University · INVeer Surendra Sai Medical College and Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

LAMP diagnosis of malaria is simple and cost-effective with acceptable sensitivity and specificity as compared to standard diagnostic modules such as microscopy, RDTs and nested PCR, and thus its deployment for onsite screening of malaria in resource-limited regions is under consideration. However, the requirement of an electricity-operated dry bath and bulky read-out unit is still a major concern. In an effort to simplify this limitation, we have developed a portable LAMP device and fluorescence readout unit which can be used in the rapid point-of-care diagnosis of malaria. We have developed a point-of-care diagnostic LAMP device that is easy to operate by a mobile application, and the results can be quantified with a fluorescent readout unit. The diagnostic performance of the device was evaluated in 90 P

Indexed as

MalariaMalaria, FalciparumHumansMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesParasitemiaPlasmodium falciparumPoint-of-Care SystemsSensitivity and SpecificityADC valuediagnosisLAMPLODparasite densityplasmodium falciparum

Identifiers

PMID36061865
PMCPMC9437306
OpenAlexW4292372826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.