Evidence map›Paper›PMID 36061859›Full record

ArticleFrontiers in cellular and infection microbiology2022

Understanding global changes of the mouse brain proteome after vaginal infection with HSV-2 using a label-free shotgun approach.

Jishuai Cheng, Qingzhen Wang, Yiwen Hu, Tangwei Mou, Jianbin Wang, Lichun Wang, Ying Zhang, Tinghua Wang, Qihan Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jishuai ChengAnimal Zoology Department, Institute of Neuroscience, Kunming Medical University, Kunming, China.
Qingzhen WangAnimal Zoology Department, Institute of Neuroscience, Kunming Medical University, Kunming, China.
Yiwen HuAnimal Zoology Department, Institute of Neuroscience, Kunming Medical University, Kunming, China.
Tangwei MouYunnan Key Laboratory of Vaccine Research and Development for Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Sciences and Peking Union Medical College, Kunming, China.
Jianbin WangYunnan Key Laboratory of Vaccine Research and Development for Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Sciences and Peking Union Medical College, Kunming, China.
Lichun WangYunnan Key Laboratory of Vaccine Research and Development for Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Sciences and Peking Union Medical College, Kunming, China.
Ying ZhangYunnan Key Laboratory of Vaccine Research and Development for Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Sciences and Peking Union Medical College, Kunming, China.
Tinghua WangAnimal Zoology Department, Institute of Neuroscience, Kunming Medical University, Kunming, China.
Qihan LiYunnan Key Laboratory of Vaccine Research and Development for Severe Infectious Diseases, Institute of Medical Biology, Chinese Academy of Medicine Sciences and Peking Union Medical College, Kunming, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNKunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herpes simplex virus type 2 (HSV-2) is a common human pathogen that establishes lifelong latency in neurons of the nervous system. The number of severe central nervous system infections caused by the virus has increased recently. However, the pathogenesis of HSV-2 infection in the nervous system is not fully understood. Here, we demonstrated global proteomic changes in the brain tissue in BALB/c mice vaginally infected with HSV-2. Data are available

Indexed as

Herpes SimplexHerpesvirus 1, HumanAnimalsBrainFemaleHerpesvirus 2, HumanHumansMiceMice, Inbred BALB CProteomeProteomicsProteomebrainHerpes simplex virus 2LFQ proteomicsneurologic diseasesynapse

Identifiers

PMID36061859
PMCPMC9433710
OpenAlexW4292181699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.