Evidence map›Paper›PMID 36061724›Full record

ArticleACS omega2022

Developmental Toxicity of Surface-Modified Gold Nanorods in the Zebrafish Model.

Zain Zaki Zakaria, Nouf N Mahmoud, Fatiha M Benslimane, Huseyin C Yalcin, Ala-Eddin Al Moustafa, Maha Al-Asmakh

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Zain Zaki ZakariaDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha 122104, Qatar.ORCID https://orcid.org/0000-0002-9656-8367
Nouf N MahmoudDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha 122104, Qatar.ORCID https://orcid.org/0000-0002-3870-7568
Fatiha M BenslimaneBiomedical Research Center, Qatar University, PO Box 2713, Doha 122104, Qatar.
Huseyin C YalcinBiomedical Research Center, Qatar University, PO Box 2713, Doha 122104, Qatar.
Ala-Eddin Al MoustafaBiomedical Research Center, Qatar University, PO Box 2713, Doha 122104, Qatar.
Maha Al-AsmakhDepartment of Biomedical Sciences, College of Health Sciences, QU Health, Qatar University, Doha 122104, Qatar.
Qatar University · QAAl-Zaytoonah University of Jordan · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundnanotechnology is one of the fastest-growing areas, and it is expected to have a substantial economic and social impact in the upcoming years. Gold particles (AuNPs) offer an opportunity for wide-ranging applications in diverse fields such as biomedicine, catalysis, and electronics, making them the focus of great attention and in parallel necessitating a thorough evaluation of their risk for humans and ecosystems. Accordingly, this study aims to evaluate the acute and developmental toxicity of surface-modified gold nanorods (AuNRs), on zebrafish (

methodsin this study, zebrafish embryos were exposed to surface-modified AuNRs at concentrations ranging from 1 to 20 μg/mL. Lethality and developmental endpoints such as hatching, tail flicking, and developmental delays were assessed until 96 h post-fertilization (hpf).

resultswe found that AuNR treatment decreases the survival rate in embryos in a dose-dependent manner. Our data showed that AuNRs caused mortality with a calculated LC50 of EC

conclusionsour results revealed that AuNR treatment at the EC

Identifiers

PMID36061724
PMCPMC9434790
OpenAlexW4292185021

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.