Evidence map›Paper›PMID 36061661›Full record

ArticleACS omega2022

Preparation and Characterization of Novel Oleogels Using Jasmine Floral Wax and Wheat Germ Oil for Oral Delivery of Curcumin.

Anashwara Babu, Gomathi Sivakumar, Anubhab Das, Deepti Bharti, Dilshad Qureshi, S K Habibullah, Anjana Satheesan, Biswaranjan Mohanty, Kunal Pal, Samarendra Maji

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Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anashwara BabuDepartment of Chemistry, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, India.
Gomathi SivakumarDepartment of Chemistry, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, India.
Anubhab DasDepartment of Chemistry, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, India.
Deepti BhartiDepartment of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela, Odisha 769008, India.
Dilshad QureshiDepartment of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela, Odisha 769008, India.
S K HabibullahInstitute of Pharmacy and Technology, Salipur, Odisha 754202, India.ORCID https://orcid.org/0000-0002-3646-7177
Anjana SatheesanDepartment of Chemistry, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, India.
Biswaranjan MohantyInstitute of Pharmacy and Technology, Salipur, Odisha 754202, India.
Kunal PalDepartment of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela, Odisha 769008, India.
Samarendra MajiDepartment of Chemistry, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, India.ORCID https://orcid.org/0000-0002-9153-2031

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oleogels (OGs) have gained a lot of interest as a delivery system for a variety of pharmaceuticals. The current study explains the development of jasmine floral wax (JFW) and wheat germ oil (WGO)-based OGs for oral drug (curcumin) delivery application. The OGs were made by dissolving JFW in WGO at 70 °C and cooling it to room temperature (25 °C). The critical gelation concentration of JFW that induces the gelation of WGO was found to be 10% (w/w). The OGs were characterized using various techniques such as Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), microscopic analysis, and mechanical test. XRD data indicated that JFW influences the crystallinity of the OGs. Among the prepared OGs, OG 17.5 showed higher crystallization in the series. Optical microscopic studies demonstrated the formation of fiber structures due to the entanglement of crystals whereas, polarized light micrographs suggested the formation of spherulites or clustered crystallite structures. The mechanical properties of the OGs increased linearly with the increase in the JFW concentration. Curcumin-loaded OGs were examined for their controlled release applications. In summary, the developed OGs were found to have the necessary features for modulating the oral delivery of curcumin.

Identifiers

PMID36061661
PMCPMC9434628

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