Evidence map›Paper›PMID 36061443›Full record

ReviewFrontiers in bioengineering and biotechnology2022

Recent advances in melt electro writing for tissue engineering for 3D printing of microporous scaffolds for tissue engineering.

Sebastian Loewner, Sebastian Heene, Timo Baroth, Henrik Heymann, Fabian Cholewa, Holger Blume, Cornelia Blume

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Review
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  4. Multi-hierarchical biofunctional polymeric biomaterial to promote wound closure.Journal of materials science. Materials in medicine · 2026
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  18. 3DMaterials today. Bio · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sebastian LoewnerInstitute of Technical Chemistry, Leibniz University Hannover, Hannover, Germany.
Sebastian HeeneInstitute of Technical Chemistry, Leibniz University Hannover, Hannover, Germany.
Timo BarothInstitute of Microelectronic Systems, Leibniz University Hannover, Hannover, Germany.
Henrik HeymannInstitute of Microelectronic Systems, Leibniz University Hannover, Hannover, Germany.
Fabian CholewaInstitute of Microelectronic Systems, Leibniz University Hannover, Hannover, Germany.
Holger BlumeInstitute of Microelectronic Systems, Leibniz University Hannover, Hannover, Germany.
Cornelia BlumeInstitute of Technical Chemistry, Leibniz University Hannover, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melt electro writing (MEW) is a high-resolution 3D printing technique that combines elements of electro-hydrodynamic fiber attraction and melts extrusion. The ability to precisely deposit micro- to nanometer strands of biocompatible polymers in a layer-by-layer fashion makes MEW a promising scaffold fabrication method for all kinds of tissue engineering applications. This review describes possibilities to optimize multi-parametric MEW processes for precise fiber deposition over multiple layers and prevent printing defects. Printing protocols for nonlinear scaffolds structures, concrete MEW scaffold pore geometries and printable biocompatible materials for MEW are introduced. The review discusses approaches to combining MEW with other fabrication techniques with the purpose to generate advanced scaffolds structures. The outlined MEW printer modifications enable customizable collector shapes or sacrificial materials for non-planar fiber deposition and nozzle adjustments allow redesigned fiber properties for specific applications. Altogether, MEW opens a new chapter of scaffold design by 3D printing.

Indexed as

3D printingelectrospinningmelt electro writingscaffoldstissue engineering

Identifiers

PMID36061443
PMCPMC9428513

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.