Evidence map›Paper›PMID 36061412›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering

Dynamic contrast-enhanced fluorescence imaging compared with MR imaging in evaluating bone perfusion during open orthopedic surgery.

Yue Tang, Jessica M Sin, I Leah Gitajn, Xu Cao, Xinyue Han, Jonathan T Elliott, Xiaohan Yu, Melanie L Christian, Logan Bateman, Theresa Chockbengboun and 3 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Yue TangThayer school of Engineering, Dartmouth College, Hanover, NH.
Jessica M SinDepartment of Radiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
I Leah GitajnDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Xu CaoThayer school of Engineering, Dartmouth College, Hanover, NH.
Xinyue HanThayer school of Engineering, Dartmouth College, Hanover, NH.
Jonathan T ElliottDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Xiaohan YuThayer school of Engineering, Dartmouth College, Hanover, NH.
Melanie L ChristianDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Logan BatemanDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Theresa ChockbengbounDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Eric R HendersonDepartment of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Brian W PogueThayer school of Engineering, Dartmouth College, Hanover, NH.
Shudong JiangThayer school of Engineering, Dartmouth College, Hanover, NH.
Dartmouth–Hitchcock Medical Center · USDartmouth College · US

Funding

Real-time Perfusion Imaging Guided Bone Debridement in Fracture Related Infection - A Precision Approach to DebridementR01AR077157 · NIAMS · DARTMOUTH-HITCHCOCK CLINIC · PI Ida L Gitajn · 2020 to 2026
$2.9M
Multimodal Fluorescence- and Imaging-Guided Surgical Navigation: Developing Methods for Subsurface, Indirect Visualization of Cancers Requiring Wide Local ExcisionK23EB026507 · NIBIB · DARTMOUTH-HITCHCOCK CLINIC · PI HENDERSON, ERIC R · 2018 to 2021
$679k
NIAMS NIH HHS R01 AR077157NIBIB NIH HHS K23 EB026507
6 · The paper itself

Abstract

ICG-based dynamic contrast-enhanced fluorescence imaging (DCE-FI) and intraoperative DCE- magnetic resonance imaging (MRI) have been carried out nearly simultaneously in three lower extremity bone infection cases to investigate the relationship between these two imaging modalities for assessing bone blood perfusion during open orthopedic surgeries. Time-intensity curves in the corresponding regions of interest of two modalities were derived for comparison. The results demonstrated that ICG-based DCE-FI has higher sensitivity to perfusion changes while DCE-MRI provides superior and supplemental depth-related perfusion information. Research applying the depth-related perfusion information derived from MRI to improve the overall analytic modeling of intraoperative DCE-FI is ongoing.

Indexed as

bone vascular perfusiondynamic contrast-enhanced fluorescence imagingdynamic contrast-enhanced magnetic resonance imagingindocyanine greenopen orthopedic surgerytime-intensity curve

Identifiers

PMID36061412
PMCPMC9430826
OpenAlexW4220760225

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.