Evidence map›Paper›PMID 36061362›Full record

SynthesisFrontiers in molecular neuroscience2022

Under or Absent Reporting of Light Stimuli in Testing of Anxiety-Like Behaviors in Rodents: The Need for Standardization.

Lorenz S Neuwirth, Michael T Verrengia, Zachary I Harikinish-Murrary, Jessica E Orens, Oscar E Lopez

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in molecular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lorenz S NeuwirthDepartment of Psychology, SUNY Old Westbury, Old Westbury, NY, United States.
Michael T VerrengiaDepartment of Psychology, SUNY Old Westbury, Old Westbury, NY, United States.
Zachary I Harikinish-MurraryDepartment of Psychology, SUNY Old Westbury, Old Westbury, NY, United States.
Jessica E OrensDepartment of Psychology, SUNY Old Westbury, Old Westbury, NY, United States.
Oscar E LopezDepartment of Psychology, SUNY Old Westbury, Old Westbury, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Behavioral neuroscience tests such as the Light/Dark Test, the Open Field Test, the Elevated Plus Maze Test, and the Three Chamber Social Interaction Test have become both essential and widely used behavioral tests for transgenic and pre-clinical models for drug screening and testing. However, as fast as the field has evolved and the contemporaneous involvement of technology, little assessment of the literature has been done to ensure that these behavioral neuroscience tests that are crucial to pre-clinical testing have well-controlled ethological motivation by the use of lighting (i.e., Lux). In the present review paper,

Indexed as

behavioral neuroscience testselevated plus mazeethologically motivated controlslight/dark testLux/lightingopen fieldrodent pre-clinical screening/testingthree chamber social interaction test

Identifiers

PMID36061362
PMCPMC9428565

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.